Humphrey R D, Harrison M J
Postgrad Med J. 1985 Dec;61(722):1039-42. doi: 10.1136/pgmj.61.722.1039.
A retrospective case note survey of 103 autopsy proven cases of cerebral infarction was carried out to assess how often a cardiac source for embolism had been correctly suspected on clinical grounds. Only 61% of 46 patients with cardiac embolic sources were so identified. Cases of rheumatic heart disease and bacterial endocarditis were more frequently identified than cases of mural thromboembolism from ischaemic heart disease. This relative failure of unaided clinical diagnostic criteria probably accounts for the discrepancy between the autopsy evidence of cardiac embolism as a cause of stroke (about 40%), and clinical studies (about 20%).
对103例经尸检证实的脑梗死病例进行了回顾性病例记录调查,以评估基于临床依据正确怀疑心脏栓塞源的频率。在46例有心脏栓塞源的患者中,只有61%被识别出来。风湿性心脏病和细菌性心内膜炎病例比缺血性心脏病引起的壁血栓栓塞病例更常被识别出来。单纯临床诊断标准的这种相对不足可能解释了作为中风病因的心脏栓塞尸检证据(约40%)与临床研究(约20%)之间的差异。