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抹茶草本提取物与2%葡萄糖酸氯己定对牙周健康状况的比较评价:一项临床微生物学研究。

Comparative Evaluation of Herbal Matcha Extract and 2% Chlorhexidine Gluconate on Periodontal Health Status: A Clinico-microbiological Study.

作者信息

Gadekar Ankita V, Dodamani Arun S, Vishwakarma Prashanth K, Agrawal Anoli S, Wankhede Saloni D, Tadas Sharvari T

机构信息

Department of Public Health Dentistry, ACPM Dental College, Dhule, Maharashtra, India, Phone: +91 9403483403, e-mail:

Department of Public Health Dentistry, ACPM Dental College, Dhule, Maharashtra, India, Orcid: https://orcid.org/0000-0002-6145-2057.

出版信息

J Contemp Dent Pract. 2025 May 1;26(5):488-492. doi: 10.5005/jp-journals-10024-3880.

DOI:10.5005/jp-journals-10024-3880
PMID:40960105
Abstract

AIM

To evaluate and compare the gingival and periodontal health status in patients after using Matcha mouthrinse and 2% chlorhexidine (CHX) gluconate mouthwash and also evaluate the efficacy of Matcha extract on and .

MATERIAL AND METHODOLOGY

It is a randomized clinical trial study with 32 adult patients having mild-to-moderate gingivitis and periodontitis. They were divided into two groups, each with 16 patients. Group A was given Matcha extract, and group B was given 2% CHX gluconate. All participants were brought to baseline by oral prophylaxis. They were asked to use their particular group mouth rinse for rinsing twice a day for 1 minute. Indices were taken at baseline, 7, 14, and 28 days. Minimal inhibitory concentration (MIC) was checked for Matcha extract on both and bacteria, and gingival crevicular fluid (GCF) was taken at baseline and after 28 days to check colony-forming units (CFUs) of the samples.

RESULTS

Matcha mouthrinse significantly reduced the inflammatory condition of gingivitis and periodontitis ( < 0.05) and is comparable with 2% CHX gluconate. evaluation of Matcha extract at various concentrations of MIC shows its effectiveness on and .

CONCLUSION

To conclude, Matcha mouthrinse may be recommended as an alternative mouthrinse for improving oral health status.

CLINICAL SIGNIFICANCE

The findings of this study suggest that Matcha mouthrinse, a natural and antioxidant-rich alternative, is effective in reducing gingival and periodontal inflammation, with outcomes comparable to the gold standard 2% CHX gluconate. Additionally, Matcha extract demonstrated antibacterial efficacy against key periodontal pathogens and . This highlights its potential as a safer, herbal-based adjunct in periodontal therapy, especially for patients seeking non-chemical or side-effect-free options for maintaining oral hygiene and preventing disease progression. How to cite this article: Gadekar AV, Dodamani AS, Vishwakarma PK, . Comparative Evaluation of Herbal Matcha Extract and 2% Chlorhexidine Gluconate on Periodontal Health Status: A Clinico-microbiological Study. J Contemp Dent Pract 2025;26(5):488-492.

摘要

目的

评估和比较使用抹茶漱口水和2%葡萄糖酸氯己定(CHX)漱口水后患者的牙龈和牙周健康状况,并评估抹茶提取物对[具体细菌名称1]和[具体细菌名称2]的疗效。

材料与方法

这是一项随机临床试验研究,纳入32例患有轻至中度牙龈炎和牙周炎的成年患者。他们被分为两组,每组16例。A组给予抹茶提取物,B组给予2%葡萄糖酸氯己定。所有参与者均通过口腔预防措施达到基线状态。要求他们每天使用各自组的漱口水漱口两次,每次1分钟。在基线、第7天、第14天和第28天采集指标。检测抹茶提取物对[具体细菌名称1]和[具体细菌名称2]的最低抑菌浓度(MIC),并在基线和第28天后采集龈沟液(GCF)以检测样本的菌落形成单位(CFU)。

结果

抹茶漱口水显著降低了牙龈炎和牙周炎的炎症状况(P<0.05),且与2%葡萄糖酸氯己定相当。对不同MIC浓度的抹茶提取物进行评估显示其对[具体细菌名称1]和[具体细菌名称2]有效。

结论

总之,抹茶漱口水可作为改善口腔健康状况的替代漱口水推荐使用。

临床意义

本研究结果表明,抹茶漱口水作为一种天然且富含抗氧化剂的替代品,在减少牙龈和牙周炎症方面有效,其效果与金标准2%葡萄糖酸氯己定相当。此外,抹茶提取物对关键牙周病原体[具体细菌名称1]和[具体细菌名称2]具有抗菌功效。这突出了其作为牙周治疗中更安全的基于草药的辅助剂的潜力,特别是对于寻求非化学或无副作用选择来维持口腔卫生和预防疾病进展的患者。如何引用本文:Gadekar AV, Dodamani AS, Vishwakarma PK, 。草药抹茶提取物和2%葡萄糖酸氯己定对牙周健康状况的比较评估:一项临床微生物学研究。《当代牙科实践杂志》2025;26(5):488 - 492。

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