Kızılyıldırım Suna, Güneri Cansu Önlen, Kandemir Tülay
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Cukurova University, Adana, Türkiye.
Department of Medical Laboratory Techniques, Medical Microbiology, Gulhane Vocational School of Health Services, University of Health Sciences Türkiye, Ankara, Türkiye.
Folia Microbiol (Praha). 2025 Sep 17. doi: 10.1007/s12223-025-01343-8.
Group B streptococcus (GBS) is a uropathogen capable of causing urinary tract infections (UTIs), although its role in male patients is not well characterized. This study aimed to investigate the capsule serotypes and clonal relationships of GBS strains isolated from male patients with urinary symptoms. A total of 69 GBS isolates from male patients admitted to Adana City Hospital were analyzed. Capsule serotypes were determined by multiplex PCR (Thermo Fisher Scientific, USA), and clonal relationships were assessed using pulsed-field gel electrophoresis (PFGE) (Bio-Rad, USA). The most common capsule serotypes identified were Ib (n = 28; 40.6%), V (n = 23; 33.3%), and III (n = 18; 26.1%). All isolates were susceptible to ampicillin and vancomycin. Resistance rates were 69.5% for ciprofloxacin, 30.4% for erythromycin, 24.6% for clindamycin, and 11.5% for tetracycline. PFGE analysis revealed that two isolates from different patients, collected on separate dates, were 100% identical, indicating possible clonal spread. In conclusion, although GBS-related UTIs are uncommon in male patients, the data obtained in this study provide valuable insights for future epidemiological research on GBS in this population.
B族链球菌（GBS）是一种能够引起尿路感染（UTI）的尿路病原体，尽管其在男性患者中的作用尚未得到充分阐明。本研究旨在调查从有尿路症状的男性患者中分离出的GBS菌株的荚膜血清型和克隆关系。对阿达纳市医院收治的男性患者中分离出的69株GBS进行了分析。通过多重聚合酶链反应（美国赛默飞世尔科技公司）确定荚膜血清型，并使用脉冲场凝胶电泳（美国伯乐公司）评估克隆关系。鉴定出的最常见荚膜血清型为Ib型（n = 28；40.6%）、V型（n = 23；33.3%）和III型（n = 18；26.1%）。所有分离株对氨苄西林和万古霉素敏感。环丙沙星耐药率为69.5%，红霉素为30.4%，克林霉素为24.6%，四环素为11.5%。脉冲场凝胶电泳分析显示，在不同日期从不同患者收集的两株分离株完全相同，表明可能存在克隆传播。总之，尽管GBS相关的尿路感染在男性患者中并不常见，但本研究获得的数据为该人群中GBS的未来流行病学研究提供了有价值的见解。
