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[巴伐利亚不同地区母亲及其新生儿体内异常的镉负荷]

[Unusual cadmium burden of mothers and their newborn infants in various areas of Bavaria].

作者信息

Schiele R, Glatzel I, Schaller K H

出版信息

Zentralbl Bakteriol Mikrobiol Hyg B. 1985 Dec;181(3-5):295-308.

PMID:4096148
Abstract

The cadmium-concentration in blood of 89 mothers and their newborns of different bavarian areas were measured by atomic absorption spectrometry. The results are within the frame of comparable recent national and international studies. A median value of 0.8 microgram Cd/l blood for the mothers resp. 0.3 microgram Cd/l for the newborns was found. The measured values ranged between 0.2 and 4.5 micrograms Cd/l for the mothers resp. 0.2 and 1.2 microgram Cd/l for the newborns. The significant difference between the cadmium-concentration in the blood samples of mothers and newborns confirms the existence of a placental barrier for cadmium. However, there was a significant correlation between the values measured for the mothers and their children (rk = 0.436). For the division into the three sub-collectives of Marktredwitz/Oberfranken, Freyung/Niederbayern und Erlangen/Mittelfranken (median values 0.6, 0.9 and 0.8 microgram Cd/l blood respectively) no significant differences could be observed. The blood-cadmium-concentrations of mothers and their newborns were not influenced by the age of the mother. An effect of the duration of the pregnancy could not be stated definitely because of a too small number of mothers with a low duration of pregnancy. A significant relationship exists between the smoking habits and the maternal blood-cadmium-concentrations. When dividing into subgroups the non-smokers show a median value of 0.6 microgram Cd/l blood, whereas the smokers have a median value of 1.1 microgram Cd/l blood. There were no significant differences between the blood-cadmium-concentrations of the newborns of smoking and non-smoking mothers. The median values were 0.3 microgram Cd/l blood for the children of non-smoking mothers respectively 0.4 microgram Cd/l blood for those of smoking mothers.

摘要

采用原子吸收光谱法测定了巴伐利亚不同地区89名母亲及其新生儿血液中的镉浓度。结果在近期国内和国际同类研究范围内。母亲血液中镉的中位数为0.8微克/升,新生儿为0.3微克/升。母亲的测量值范围在0.2至4.5微克/升之间,新生儿在0.2至1.2微克/升之间。母亲和新生儿血液样本中镉浓度的显著差异证实了镉存在胎盘屏障。然而,母亲及其子女的测量值之间存在显著相关性(rk = 0.436)。对于分为马克特雷德维茨/上弗兰肯、弗赖翁/下拜仁和埃尔朗根/中弗兰肯三个子群体(中位数分别为0.6、0.9和0.8微克/升血液),未观察到显著差异。母亲及其新生儿的血镉浓度不受母亲年龄影响。由于孕期短的母亲数量过少,无法明确说明孕期长短的影响。吸烟习惯与母亲血镉浓度之间存在显著关系。分为亚组时,不吸烟者血镉中位数为0.6微克/升,吸烟者为1.1微克/升。吸烟和不吸烟母亲的新生儿血镉浓度无显著差异。不吸烟母亲的孩子血镉中位数为0.3微克/升,吸烟母亲的孩子为0.4微克/升。

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