Nebel Lisa, Le Butt Timothy, Sell Christian, Herrmann-Lingen Christoph, Broschmann Daniel
Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.
International Psychoanalytic University Berlin, Berlin, Germany.
Health Qual Life Outcomes. 2025 Sep 18;23(1):84. doi: 10.1186/s12955-025-02423-6.
To explore the lived experiences of people with chronic heart disease (PCHD).
Systematic meta-synthesis.
Following preregistration on PROSPERO, a systematic literature search was conducted in PubMed, PsycInfo, PsycArticles, and PSYNDEX between February 2023 and March 2024. Articles were assessed for eligibility based on predefined criteria and evaluated for methodological quality using a modified CASP tool. The results of the included primary studies were weighted according to their methodological quality and synthesized using Interpretative Phenomenological Analysis. The reporting adheres to PRISMA and ENTREQ guidelines.
The analysis of 43 articles revealed an overarching theme: “The broken flow of life.” This theme illustrates the disruption of normalcy, as perceived by patients through distinct dimensions. These dimensions are represented by the four subthemes: (1) I no longer feel safe in my body, (2) Suddenly, I have less of a future, (3) My identity feels shattered, and (4) My disease strains my relationships.
The findings suggest that PCHD perceive their condition as a profound disruption of normalcy, affecting bodily, relational, and psychological dimensions that extend beyond established HRQOL measures.
The findings have direct implications for the assessment of HRQOL in medicine. To adequately evaluate holistic treatments, a deeper understanding of how the disease affects life planning and future perspectives is essential. Consequently, established HRQOL measures may need to be extended both in content and temporal scope to capture these broader impacts.
The online version contains supplementary material available at 10.1186/s12955-025-02423-6.
探讨慢性心脏病患者的生活经历。
系统的元综合分析。
在PROSPERO上预先注册后，于2023年2月至2024年3月期间在PubMed、PsycInfo、PsycArticles和PSYNDEX中进行了系统的文献检索。根据预定义标准评估文章的 eligibility，并使用改良的CASP工具评估方法学质量。纳入的原始研究结果根据其方法学质量进行加权，并使用解释性现象学分析进行综合。报告遵循PRISMA和ENTREQ指南。
对43篇文章的分析揭示了一个总体主题：“生活的断裂流”。这个主题说明了患者通过不同维度所感知到的常态的破坏。这些维度由四个子主题表示：(1) 我在自己的身体里不再感到安全，(2) 突然，我的未来变得更少了，(3) 我的身份感觉破碎了，(4) 我的疾病使我的人际关系紧张。
研究结果表明，慢性心脏病患者将他们的状况视为对常态的深刻破坏，影响身体、关系和心理维度，这些维度超出了既定的健康相关生活质量测量范围。
这些发现对医学中健康相关生活质量的评估有直接影响。为了充分评估整体治疗，深入了解疾病如何影响生活规划和未来展望至关重要。因此，既定的健康相关生活质量测量可能需要在内容和时间范围上进行扩展，以捕捉这些更广泛的影响。
在线版本包含可在10.1186/s12955-025-02423-6获取的补充材料。
