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人胃和甲状腺中含拉塞尔小体浆细胞的超微结构

Ultrastructure of plasma cells containing Russell bodies in human stomach and thyroid.

作者信息

Gray A, Doniach I

出版信息

J Clin Pathol. 1970 Oct;23(7):608-12. doi: 10.1136/jcp.23.7.608.

DOI:10.1136/jcp.23.7.608
PMID:4098418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476846/
Abstract

The fine structure is illustrated of plasma cells containing Russell bodies. The material is from chronic inflammatory cell infiltrates in human gastric mucosa and thyroid glands in Graves' disease and Hashimoto's thyroiditis. It is noted that the Russell bodies lie in distended cisternae of rough endoplasmic reticulum and are easily distinguished from less electron-dense ;secretory granules' covered by a smooth membrane that are situated in the Golgi complex.

摘要

含拉塞尔小体的浆细胞的精细结构得以呈现。材料取自人类胃黏膜的慢性炎性细胞浸润以及格雷夫斯病和桥本甲状腺炎患者的甲状腺。值得注意的是，拉塞尔小体位于粗面内质网的扩张池内，且易于与位于高尔基体复合体中、被光滑膜覆盖的电子密度较低的“分泌颗粒”区分开来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/e89faae81f2f/jclinpath00087-0059-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/b3291321e873/jclinpath00087-0057-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/911a78407fd3/jclinpath00087-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/ab4f3d45c07a/jclinpath00087-0058-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/9ff651a3755c/jclinpath00087-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/e89faae81f2f/jclinpath00087-0059-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/b3291321e873/jclinpath00087-0057-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/911a78407fd3/jclinpath00087-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/ab4f3d45c07a/jclinpath00087-0058-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/9ff651a3755c/jclinpath00087-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2959/476846/e89faae81f2f/jclinpath00087-0059-b.jpg

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引用本文的文献

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Localized accumulation of kappa restricted Russell body-containing plasma cells in tonsil.扁桃体中κ受限的含拉塞尔小体浆细胞的局部聚集。
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Russell body gastritis with Dutcher bodies evaluated using magnification endoscopy.使用放大内镜评估伴有达彻小体的拉塞尔小体胃炎。
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Helicobacter pylori-negative Russell body gastritis: does the diagnosis call for screening for plasmacytic malignancies, especially multiple myeloma?

本文引用的文献

1
The Nature of Russell Bodies and Kurloff Bodies: Observations on the Cytochemistry of Plasma Cells and Reticulum Cells.拉塞尔小体和库尔洛夫小体的本质：关于浆细胞和网状细胞细胞化学的观察
J Clin Pathol. 1949 May;2(2):81-90. doi: 10.1136/jcp.2.2.81.
2
Light and electron microscopic correlation of the periodic acid-Schiff reaction in the human plasma cell.人浆细胞中高碘酸-希夫反应的光镜与电镜相关性研究
Am J Pathol. 1962 Mar;40(3):285-96.
3
The fine structure of connective tissue. II. The plasma cell.
幽门螺杆菌阴性的拉塞尔小体胃炎：该诊断是否需要筛查浆细胞恶性肿瘤，尤其是多发性骨髓瘤？
BMJ Case Rep. 2014 Mar 26;2014:bcr2013202672. doi: 10.1136/bcr-2013-202672.
4
Aggregates, crystals, gels, and amyloids: intracellular and extracellular phenotypes at the crossroads of immunoglobulin physicochemical property and cell physiology.聚集体、晶体、凝胶和淀粉样蛋白：处于免疫球蛋白物理化学性质与细胞生理学交叉点的细胞内和细胞外表型。
Int J Cell Biol. 2013;2013:604867. doi: 10.1155/2013/604867. Epub 2013 Mar 5.
5
Russell body gastritis associated with Helicobacter pylori infection: a case report.与幽门螺杆菌感染相关的拉塞尔小体胃炎：一例报告
J Clin Pathol. 2006 Dec;59(12):1316-9. doi: 10.1136/jcp.2005.032185.
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Selective presence of ubiquitin in intracellular inclusions.泛素在细胞内包涵体中的选择性存在。
Am J Pathol. 1989 Mar;134(3):505-13.
7
Hashimoto's thyroiditis with immunoblastic lymphadenopathy and unusual "macaroni cells".伴有免疫母细胞性淋巴结病及异常“通心粉细胞”的桥本甲状腺炎
Can Med Assoc J. 1977 Jul 9;117(1):41-3.
8
[Electron microscopical investigation of rhinoscleroma (author's transl)].鼻硬结病的电子显微镜研究（作者译）
Arch Dermatol Res (1975). 1975 Dec 31;254(3):263-74. doi: 10.1007/BF00557968.
Exp Mol Pathol. 1962 Dec;1:535-53. doi: 10.1016/0014-4800(62)90041-2.
4
[Contrast phase and electron microscopy study of plasmocytes. III. Plasmocytes with Russell bodies and crystals].
Rev Hematol. 1958 Jan-Mar;13(1):61-78.
5
Observations on the formation and nature of Russell bodies.关于拉塞尔小体的形成及性质的观察
Br J Exp Pathol. 1954 Aug;35(4):365-76.
6
Ultrastructural localization of antibody in differentiating plasma cells.分化浆细胞中抗体的超微结构定位
J Exp Med. 1968 Jan 1;127(1):109-18. doi: 10.1084/jem.127.1.109.