Fukuhara S, Klingmüller G
Arch Dermatol Res (1975). 1975 Dec 31;254(3):263-74. doi: 10.1007/BF00557968.
A boy from Togo with a resistent Rhinoscleroma was observed. The specific granuloma was examinated by histological and electron microscopic methods. The plasma cells form fibrillary material or guttate Russel bodies in the rough endoplasmatic reticulum. The morphology of Mikulicz-cells and Klebsiella rhinoscleromatis is described. The cells are supposed to be (histiocytic) macrophages. The surface of the germs is coated with a fimbria-like radiate substance which in the vacuoles of the cells is crosslinked. This material could be the eliciting antigen for the formation of Russel bodies. These bodies then may represent immune substances bound within the cell.
观察到一名来自多哥的患有抗药鼻硬结病的男孩。通过组织学和电子显微镜方法对特异性肉芽肿进行了检查。浆细胞在内质网粗糙面形成纤维状物质或滴状鲁塞尔小体。描述了米库利奇细胞和鼻硬结克雷伯菌的形态。这些细胞被认为是（组织细胞性）巨噬细胞。细菌表面覆盖有类似菌毛的放射状物质，该物质在细胞液泡中交联。这种物质可能是形成鲁塞尔小体的引发抗原。这些小体可能代表细胞内结合的免疫物质。
