Rezvan Mahsa, Hossini Seyed Erfan, Sarmast Kimia, Khamesipour Faham
TUM School of Medicine and Health, Institute of Pathology Technical University of Munich Munich Germany.
Food and Drug Administration of Lorestan University of Medical Sciences Khorramabad Iran.
Health Sci Rep. 2025 Sep 22;8(9):e71251. doi: 10.1002/hsr2.71251. eCollection 2025 Sep.
Gastric cancer is a global health concern with high morbidity and mortality. This systematic review evaluates the potential of plant extracts in the prevention of gastric cancer by analyzing their bioactive mechanisms.
A total of 62 studies-including in vitro, in vivo, and clinical trials-were analyzed, focusing on their antiproliferative, proapoptotic, antiangiogenic, and anti-inflammatory properties.
Extracts such as , , and showed significant promise.
Despite these findings, issues surrounding bioavailability, dosing standardization, and long-term safety require further investigation before clinical translation.
胃癌是一个全球性的健康问题，发病率和死亡率都很高。本系统评价通过分析植物提取物的生物活性机制，评估其在预防胃癌方面的潜力。
共分析了62项研究，包括体外、体内和临床试验，重点关注其抗增殖、促凋亡、抗血管生成和抗炎特性。
诸如 、 和 等提取物显示出显著的前景。
尽管有这些发现，但在临床转化之前，围绕生物利用度、给药标准化和长期安全性等问题仍需进一步研究。
