Chalupczak Natalia V, Lipner Shari R
Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, IL 60064, USA.
Department of Dermatology, Weill Cornell Medicine, New York, NY 10021, USA.
J Fungi (Basel). 2025 Sep 10;11(9):662. doi: 10.3390/jof11090662.
folliculitis, previously known as Pityrosporum folliculitis, is a common yet frequently misdiagnosed dermatologic condition caused by yeast overgrowth in hair follicles. Its monomorphic, pruritic papules and pustules closely mimic acne vulgaris, often leading to inappropriate antibiotic use. This review summarizes current evidence on the epidemiology, clinical presentation, diagnostic challenges, and management of folliculitis. A high index of clinical suspicion is critical in patients with recalcitrant acneiform eruptions. Diagnosis is supported by dermoscopy, potassium hydroxide preparation, Wood's lamp, and response to antifungal therapy. Topical and oral antifungal agents are highly effective although relapses are common and access to off-label treatments may be limited. Greater awareness of the distinct clinical features of folliculitis and treatment response can improve diagnostic accuracy and enhance patient outcomes.
毛囊性皮肤炎，以前称为糠秕孢子菌性毛囊炎，是一种常见但常被误诊的皮肤病，由毛囊内酵母菌过度生长引起。其单一形态、瘙痒性丘疹和脓疱与寻常痤疮极为相似，常导致不恰当使用抗生素。本综述总结了目前关于毛囊性皮肤炎的流行病学、临床表现、诊断挑战及治疗的证据。对于患有顽固性痤疮样皮疹的患者，高度的临床怀疑至关重要。皮肤镜检查、氢氧化钾制剂、伍德灯检查及对抗真菌治疗的反应有助于诊断。局部和口服抗真菌药物非常有效，尽管复发很常见，且获取非标签治疗药物的途径可能有限。提高对毛囊性皮肤炎独特临床特征及治疗反应的认识，可提高诊断准确性并改善患者预后。
