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兔外周血淋巴细胞的膜相关免疫球蛋白:b位点的等位基因排斥

Membrane-associated immunoglobulin of rabbit peripheral blood lymphocytes: allelic exclusion at the b locus.

作者信息

Davie J M, Paul W E, Mage R G, Goldman M B

出版信息

Proc Natl Acad Sci U S A. 1971 Feb;68(2):430-4. doi: 10.1073/pnas.68.2.430.

Abstract

Light chain allotypic determinants were demonstrated on the surface of peripheral blood lymphocytes of rabbits. By means of a combined immunofluorescent and autoradiographic technique, a great majority of the individual lymphocytes of rabbits heteroxygous at the b locus were shown to have detectable quantities of only one allotype. A small proportion of lymphocytes appeared to possess both allelic forms of L chains.

摘要

在兔外周血淋巴细胞表面证实有轻链同种异型决定簇。通过免疫荧光和放射自显影相结合的技术,发现b位点杂合的兔的绝大多数单个淋巴细胞仅含有可检测量的一种同种异型。一小部分淋巴细胞似乎同时拥有L链的两种等位基因形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb0c/388954/d18596f99736/pnas00077-0187-a.jpg

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