Kwon Noh Eun, Brown Nicolas, Jun Jong Hwa, Bang Seung Pil
Department of Ophthalmology, Keimyung University School of Medicine, Dongsan Medical Center, Daegu 42601, Republic of Korea.
Ovitz, Rochester, NY 14604, USA.
J Clin Med. 2025 Sep 22;14(18):6688. doi: 10.3390/jcm14186688.
: Intraoperative aberrometry has gained clinical relevance in correcting aberrations during cataract and corneal refractive surgeries. As wavefront aberrations are typically measured with patients seated, while surgeries are performed supine, this study aimed to compare ocular aberrations between seated and supine positions, using a hand-held Hartmann-Shack aberrometer. : Total ocular wavefront aberrations were measured five times consecutively from cyclopledged eyes for a 6 mm pupil, under three conditions: (1) seated with a holder-fixed mode (reference), (2) seated with a hand-held mode, and (3) supine with a hand-held mode. Condition 2 was included to assess potential measurement errors from the hand-held mode. Repeatability was assessed using the standard deviation of repeated measurements (Srm) and the intraclass correlation coefficient (ICC). Differences among the three conditions were analyzed to evaluate the effects of positional change and hand-held stability on ocular wavefront aberration measurements. : Eighteen healthy subjects (36 eyes) were enrolled. The Srms for the sphere were 0.37, 0.38, and 0.40 diopters (D); and for the cylinder, 0.10, 0.10, and 0.11 D, with no significant differences across conditions. ICC values exceeded 0.9 for both lower-order aberrations (LOAs) and higher-order aberrations (HOAs), indicating excellent repeatability. The mean root mean square HOAs (HOA_RMS) were 0.48, 0.49, and 0.45 µm, with no statistically significant differences by position ( = 0.913) or measurement mode ( = 0.966). : The hand-held Hartmann-Shack aberrometer demonstrated satisfactory repeatability for LOAs and HOAs. Supine measurements did not differ from seated, supporting the feasibility of extending preoperative results to intraoperative aberrometry, regardless of positional differences.
术中像差仪在白内障和角膜屈光手术中校正像差方面已具有临床相关性。由于波前像差通常是在患者坐姿时测量的，而手术是在仰卧位进行的，本研究旨在使用手持式哈特曼-夏克像差仪比较坐姿和仰卧位时的眼像差。：在三种情况下，对散瞳眼的6毫米瞳孔连续测量五次全眼波前像差：（1）坐姿固定支架模式（参考），（2）坐姿手持模式，（3）仰卧位手持模式。纳入条件2是为了评估手持模式下的潜在测量误差。使用重复测量的标准差（Srm）和组内相关系数（ICC）评估重复性。分析三种情况之间的差异，以评估位置变化和手持稳定性对眼波前像差测量的影响。：招募了18名健康受试者（36只眼）。球镜的Srm分别为0.37、0.38和0.40屈光度（D）；柱镜的Srm分别为0.10、0.10和0.11 D，不同条件之间无显著差异。低阶像差（LOA）和高阶像差（HOA）的ICC值均超过0.9，表明重复性极佳。平均高阶像差均方根（HOA_RMS）分别为0.48、0.49和0.45 µm，位置（=0.913）或测量模式（=0.966）对其无统计学显著差异。：手持式哈特曼-夏克像差仪对低阶像差和高阶像差显示出令人满意的重复性。仰卧位测量与坐姿测量无差异，这支持了无论位置差异如何，将术前结果扩展到术中像差测量的可行性。
