铜绿假单胞菌中β-内酰胺类抗生素耐药性相关因素。
Factors involved in beta-lactam antibiotic resistance in Pseudomonas aeruginosa.
作者信息
Ohmori H, Azuma A, Suzuki Y, Hashimoto Y
出版信息
Antimicrob Agents Chemother. 1977 Oct;12(4):537-9. doi: 10.1128/AAC.12.4.537.
Abstract
A temperature-sensitive mutant, strain SS, which is assumed to be devoid of beta-lactamase activity and deficient in a permeability barrier to antibiotics, was isolated from a beta-lactamase-less mutant, strain L-2, derived from Pseudomonas aeruginosa IFO 3080. By comparing the beta-lactam antibiotic susceptibility between strains IFO 3080, L-2, and SS, the involvement of both beta-lactamase and a permeability barrier in determining the beta-lactam antibiotic resistance was estimated.
摘要
从源自铜绿假单胞菌IFO 3080的无β-内酰胺酶突变株L-2中分离出一种温度敏感突变株SS，该突变株被认为缺乏β-内酰胺酶活性且对抗生素的通透性屏障存在缺陷。通过比较IFO 3080、L-2和SS菌株对β-内酰胺抗生素的敏感性，评估了β-内酰胺酶和通透性屏障在决定β-内酰胺抗生素抗性中的作用。
相似文献
1
Factors involved in beta-lactam antibiotic resistance in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 1977 Oct;12(4):537-9. doi: 10.1128/AAC.12.4.537.
2
Resistance of Pseudomonas aeruginosa to new beta-lactamase-resistant beta-lactams.
Antimicrob Agents Chemother. 1984 Oct;26(4):485-8. doi: 10.1128/AAC.26.4.485.
3
Roles of porin and beta-lactamase in beta-lactam resistance of Pseudomonas aeruginosa.
Rev Infect Dis. 1988 Jul-Aug;10(4):770-5. doi: 10.1093/clinids/10.4.770.
4
The mechanism of resistance of Pseudomonas aeruginosa to beta-lactam antibiotics and clinical significance.
J Huazhong Univ Sci Technolog Med Sci. 2002;22(4):339-42. doi: 10.1007/BF02896781.
5
Occurrence of antipseudomonal beta-lactams and aminoglycosides resistance in Pseudomonas aeruginosa during therapy.
Microbiologica. 1987 Jan;10(1):103-10.
6
Resistance of Pseudomonas aeruginosa to beta-lactam antibiotics.
Folia Microbiol (Praha). 1987;32(4):290-6. doi: 10.1007/BF02877216.
7
The emergence of beta-lactam resistance among strains of Enterobacter cloacae and Pseudomonas aeruginosa.
Pediatr Infect Dis J. 1989 Sep;8(9 Suppl):S100-3; discussion S128-32. doi: 10.1097/00006454-198909001-00002.
8
Simple method to determine beta-lactam resistance phenotypes in Pseudomonas aeruginosa using the disc agar diffusion test.
J Antimicrob Chemother. 2005 Oct;56(4):657-64. doi: 10.1093/jac/dki303. Epub 2005 Sep 6.
9
Defects in Efflux (), β-Lactamase (), and Lipopolysaccharide Transport () Genes Mediate Antibiotic Hypersusceptibility of Strain Z61.
Antimicrob Agents Chemother. 2019 Jun 24;63(7). doi: 10.1128/AAC.00784-19. Print 2019 Jul.
10
Diversity of β-lactam resistance mechanisms in cystic fibrosis isolates of Pseudomonas aeruginosa: a French multicentre study.
J Antimicrob Chemother. 2013 Aug;68(8):1763-71. doi: 10.1093/jac/dkt115. Epub 2013 Apr 29.
引用本文的文献
1
Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin.
Antimicrob Agents Chemother. 1994 Aug;38(8):1732-41. doi: 10.1128/AAC.38.8.1732.
2
Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria.
Microbiol Rev. 1983 Sep;47(3):361-409. doi: 10.1128/mr.47.3.361-409.1983.
本文引用的文献
1
A NONSPECIFIC INCREASE IN PERMEABILITY IN ESCHERICHIA COLI PRODUCED BY EDTA.
Proc Natl Acad Sci U S A. 1965 Apr;53(4):745-50. doi: 10.1073/pnas.53.4.745.
2
Role of lipopolysaccharides in antibiotic resistance and bacteriophage adsorption of Escherichia coli K-12.
J Bacteriol. 1971 Mar;105(3):968-75. doi: 10.1128/jb.105.3.968-975.1971.
3
Murein and the outer penetration barrier of Escherichia coli K-12, Proteus mirabilis, and Pseudomonas aeruginosa.
J Bacteriol. 1972 Dec;112(3):1364-74. doi: 10.1128/jb.112.3.1364-1374.1972.
4
The beta-lactamases of gram-negative bacteria and their possible physiological role.
Adv Microb Physiol. 1973;9:31-88. doi: 10.1016/s0065-2911(08)60376-8.
5
Mutant of Pseudomonas aeruginosa 18S that synthesizes type Id beta-lactamase constitutively.
J Bacteriol. 1976 Sep;127(3):1585-6. doi: 10.1128/jb.127.3.1585-1586.1976.
6
Indirect method for assessing the penetration of beta-lactamase-nonsusceptible penicillins and cephalosporins in Escherichia coli strains.
Antimicrob Agents Chemother. 1976 Aug;10(2):215-8. doi: 10.1128/AAC.10.2.215.
7
Isolation and properties of beta-lactamase-less mutants from clinically important gram-negative bacteria.
J Antibiot (Tokyo). 1977 Mar;30(3):267-9. doi: 10.7164/antibiotics.30.267.
8
Resistance of Pseudomonas aeruginosa to antimicrobial drugs.
Prog Med Chem. 1975;12:333-93. doi: 10.1016/s0079-6468(08)70180-2.
Zotero 插件