通过细胞毒性试验在人淋巴细胞表面检测到的免疫球蛋白M的独特型决定簇。
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays.
作者信息
Wernet P, Feizi T, Kunkel H G
出版信息
J Exp Med. 1972 Sep 1;136(3):650-5. doi: 10.1084/jem.136.3.650.
Abstract
The complement-mediated cytotoxicity assay has been used to demonstrate surface immunoglobulin determinants on human peripheral blood lymphocytes. In two individuals with monoclonal serum IgM components, idiotypic antisera demonstrated similar components on a significant proportion of the peripheral blood lymphocytes.
摘要
补体介导的细胞毒性试验已被用于证明人外周血淋巴细胞表面的免疫球蛋白决定簇。在两名具有单克隆血清IgM成分的个体中，独特型抗血清在相当比例的外周血淋巴细胞上显示出类似成分。
相似文献
1
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays.
J Exp Med. 1972 Sep 1;136(3):650-5. doi: 10.1084/jem.136.3.650.
2
Independence of HL-A antigens and immunoglobulin determinants on the surface of human lymphoid cells.
Eur J Immunol. 1972 Jun;2(3):297-300. doi: 10.1002/eji.1830020323.
3
Beta-2-microglobulin. Part of the HL-A molecule in the cell membrane.
Tissue Antigens. 1974;4(1):83-94. doi: 10.1111/j.1399-0039.1974.tb00229.x.
4
[Demonstration of immunoglobulin determinants on human lymphocytes].
Allerg Immunol (Leipz). 1973;19(2-4):219-22.
5
Association between the beta-2-m-HL-A molecule and membrane structures responsible for lymphocyte activation.
Transplant Rev. 1974;21(0):35-52. doi: 10.1111/j.1600-065x.1974.tb01545.x.
6
Occurrence of surface IgM, IgD, and free light chains of human lymphocytes.
J Exp Med. 1974 Feb 1;139(2):451-6. doi: 10.1084/jem.139.2.451.
7
Immunoglobulin and theta-bearing murine leukemias and lymphomas.
J Immunol. 1972 May;108(5):1146-51.
8
Protective and cellular immune responses to idiotypic determinants on cells from a spontaneous lymphoma of NZB-NZW F1 mice.
J Exp Med. 1974 Dec 1;140(6):1547-58. doi: 10.1084/jem.140.6.1547.
9
[Membrane immunoglobulins on the surface of normal lymphocytes].
Nouv Presse Med. 1973 Feb 3;2(5):283-8.
10
Immunoglobulin light chain determinants on unstimulated and stimulated human blood lymphocytes, assayed by indirect immunofluorescence.
Immunology. 1971 Jun;20(6):1099-111.
引用本文的文献
1
Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human mu-chain, with identical N-termini and different C-termini.
J Exp Med. 1980 Aug 1;152(2):463-8. doi: 10.1084/jem.152.2.463.
2
Mechanisms of tumour cell escape encountered in treating lymphocytic leukaemia with anti-idiotypic antibody.
Br J Cancer. 1984 May;49(5):547-57. doi: 10.1038/bjc.1984.88.
3
Treatment of lymphoid tumors with anti-idiotype antibodies.
Springer Semin Immunopathol. 1983;6(1):99-115. doi: 10.1007/BF01857369.
4
A lymphoproliferative disorder of the large granular lymphocytes with natural killer activity.
J Clin Immunol. 1983 Jan;3(1):30-41. doi: 10.1007/BF00919136.
5
Surface immunoglobulins on blood lymphocytes of normal and immunodeficient persons studied by the mixed antiglobulin method.
Immunology. 1973 Oct;25(4):573-81.
6
Idiotypic specificity of surface immunoglobulin and the maturation of leukemic bone-marrow-derived lymphocytes.
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4487-90. doi: 10.1073/pnas.71.11.4487.
7
A depression of cell-mediated immunity to measles antigen in patients with systemic lupus erythematosus.
J Exp Med. 1974 Apr 1;139(4):1019-24. doi: 10.1084/jem.139.4.1019.
8
Monoclonal lymphocyte population in human plasma cell myeloma.
Clin Exp Immunol. 1974 Jul;17(3):371-84.
9
Protective and cellular immune responses to idiotypic determinants on cells from a spontaneous lymphoma of NZB-NZW F1 mice.
J Exp Med. 1974 Dec 1;140(6):1547-58. doi: 10.1084/jem.140.6.1547.
10
Membrane immunoglobulins of B lymphocytes: inability to detect certain characteristic IgM and IgD antigens.
J Exp Med. 1974 Oct 1;140(4):895-903. doi: 10.1084/jem.140.4.895.
本文引用的文献
1
Lymphocytes in human immunodeficiency states: a study of membrane-associated immunoglobulins.
Eur J Immunol. 1971 Dec;1(6):482-6. doi: 10.1002/eji.1830010615.
2
MICRODROPLET ASSAY OF HUMAN SERUM CYTOTOXINS.
Nature. 1964 Dec 5;204:998-1000. doi: 10.1038/204998b0.
3
The cytotoxic effect on human lymphocytes of rabbit antisera to human Fc (IgG).
Transplantation. 1971 Dec;12(6):468-71. doi: 10.1097/00007890-197112000-00009.
4
Immunochemical studies on blood groups. XLVII. The I antigen complex--precursors in the A, B, H, Lea, and leb blood group system--hemagglutination-inhibition studies.
J Exp Med. 1971 Jan 1;133(1):39-52. doi: 10.1084/jem.133.1.39.
5
The lymphocytotoxic reaction: the mechanism of rabbit complement action.
J Immunol. 1971 Oct;107(4):939-47.
6
Immunoglobulin spots on the surface of rabbit lymphocytes.
J Exp Med. 1970 Nov;132(5):1001-18. doi: 10.1084/jem.132.5.1001.
7
Immunoglobulins on the surface of lymphoid cells in Waldenström's macroglobulinemia.
J Clin Invest. 1972 Mar;51(3):701-5. doi: 10.1172/JCI106858.
8
Surgace IgM specificity on cells derived from a Burkitt's lymphoma.
Lancet. 1967 Nov 18;2(7525):1068-70. doi: 10.1016/s0140-6736(67)90340-6.
9
Selective cytotoxicity of anti-kappa serum for B lymphocytes.
Nat New Biol. 1972 May 3;237(70):18-20. doi: 10.1038/newbio237018a0.
10
Immunoglobulin and other surface antigens of cells of the immune system.
J Exp Med. 1971 Oct 1;134(4):815-32. doi: 10.1084/jem.134.4.815.
Zotero 插件