Farkas Balint, Papp Kata Szilvia, Kolumban Szilard, Kovacs Kalman, Bodis Jozsef, Fazekas Gabor
Department of Obstetrics and Gynecology, University of Pécs Medical School, Pécs, Hungary.
National Laboratory on Human Reproduction, Pécs, Hungary.
Clin Transplant. 2025 Nov;39(11):e70356. doi: 10.1111/ctr.70356.
Uterus transplantation (UTx) is a novel and clinically successful treatment option for patients with absolute uterine factor infertility (AUFI) who wish to achieve biological motherhood. Although over 100 UTx procedures have been performed at 20 centers worldwide in the past decade, the procedure remains relatively unknown-even among healthcare professionals. This study aimed to assess public opinion regarding UTx and to identify knowledge gaps in the Hungarian population's awareness and perception of the procedure.
This prospective study was conducted between December 18, 2024, and January 5, 2025, via an online survey involving 2896 participants. A final representative sample of 1500 individuals was selected using an iterative mathematical weighting method, adjusted to the 2022 Hungarian census data. The sample was representative of the Hungarian internet-using population aged 18-70 years in terms of age, gender, education level, and place of residence. The 24-item questionnaire assessed participants' views on organ donation, transplantation, infertility, surrogacy, and UTx.
Most respondents (77%; 1155/1500) supported UTx (strongly agree: 44%, 660/1500; agree: 33%, 495/1500). Among participants personally affected by fertility issues, 84% (152/181) expressed support, with 51% (92/181) strongly agreeing that UTx should be offered. Only 4% of the total samples opposed the procedure. Notably, just 15% of respondents were previously aware that UTx had been performed internationally.
This online survey demonstrates substantial public approval for UTx in Hungary, particularly among individuals affected by infertility. However, public awareness of the procedure remains limited, indicating a need for increased education and communication to improve general knowledge on the topic.
子宫移植（UTx）是一种新颖且临床成功的治疗选择，适用于那些希望实现亲生母亲身份的绝对子宫因素不孕症（AUFI）患者。尽管在过去十年中全球20个中心已进行了100多例子宫移植手术，但该手术仍然相对鲜为人知，即使在医疗保健专业人员中也是如此。本研究旨在评估公众对子宫移植的看法，并确定匈牙利人群在该手术的认知和观念方面的知识差距。
这项前瞻性研究于2024年12月18日至2025年1月5日通过在线调查进行，共有2896名参与者。使用迭代数学加权方法，根据2022年匈牙利人口普查数据进行调整，最终选取了1500人的代表性样本。该样本在年龄、性别、教育水平和居住地点方面代表了18至70岁使用互联网的匈牙利人群。这份包含24个项目的问卷评估了参与者对器官捐赠、移植、不孕症、代孕和子宫移植的看法。
大多数受访者（77%；1155/1500）支持子宫移植（强烈同意：44%，660/1500；同意：33%，495/1500）。在受生育问题影响的参与者中，84%（152/181）表示支持，其中51%（92/181）强烈同意应提供子宫移植。在总样本中，只有4%的人反对该手术。值得注意的是，只有15%的受访者之前知道子宫移植已在国际上开展。
这项在线调查表明匈牙利公众对子宫移植普遍表示认可，尤其是在受不孕症影响的人群中。然而，公众对该手术的认知仍然有限，这表明需要加强教育和沟通，以提高对这一主题的普遍认识。
