Vaccarino Viola, Prescott Eva, Shah Amit J, Bremner J Douglas, Raggi Paolo, Dobiliene Olivija, Gale Chris P, Bugiardini Raffaele
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
Department of Medicine, Emory University School of Medicine, Atlanta, USA.
Lancet Reg Health Eur. 2025 Aug 21;56:101373. doi: 10.1016/j.lanepe.2025.101373. eCollection 2025 Sep.
Mental health disorders are highly prevalent and are associated with significant morbidity, disability, and reduced life expectancy. A key contributor to this disparity is the increased risk of cardiovascular disease (CVD), which is partially driven by inequalities in social determinants of health, healthcare access, and quality of care. To address this challenge, The Lancet Regional Health-Europe convened experts to evaluate the current state of knowledge on inequalities and disparities in cardiovascular health among people with mental health disorders and propose recommendations to address these disparities. This Series paper aims to raise awareness of the disparities in CVD and health-care quality faced by individuals with common mental health conditions such as major depression, anxiety disorders, schizophrenia, bipolar disorder, and posttraumatic stress disorder. There is an urgent need for increased investment, intervention, and research to address the burden of CVD in these populations. Effective management of the comorbidity between mental health disorders and CVD requires an integrated and holistic approach to clinical care that addresses shared risk factors and the complex interactions between physical and mental health.
精神健康障碍极为普遍，且与高发病率、残疾及预期寿命缩短相关。造成这种差异的一个关键因素是心血管疾病（CVD）风险增加，这部分是由健康的社会决定因素、医疗保健可及性及医疗质量方面的不平等所驱动。为应对这一挑战，《柳叶刀·欧洲区域健康》召集专家评估关于精神健康障碍患者心血管健康方面不平等和差异的现有知识状况，并提出解决这些差异的建议。本系列文章旨在提高人们对患有重度抑郁症、焦虑症、精神分裂症、双相情感障碍和创伤后应激障碍等常见精神健康状况的个体所面临的心血管疾病和医疗质量差异的认识。迫切需要增加投资、进行干预和开展研究，以应对这些人群中的心血管疾病负担。有效管理精神健康障碍与心血管疾病之间的共病需要一种综合、全面的临床护理方法，以解决共同的风险因素以及身心健康之间的复杂相互作用。
