Hough A J, Mottram F C, Sokoloff L
Am J Pathol. 1973 Oct;73(1):201-16.
Amianthoid (asbestoid) fibers in aging human costal cartilage are shown to be collagenous both by their electron microscopic appearance and solubilization by clostridial collagenase. The fibers differ morphologically from collagen of dermis, synovium, tendon, fibrocartilage and hyaline articular cartilage in dimension, contour and arrangement. They measure up to 1 mu in width, and their period length is 560 to 620 A. Their thickness, straightness and parallel organization suggest that amianthoid fibers are rigid. Their stability in the face of the preparative technics suggests that cohesive forces rather than spatial apposition through depletion of ground substance operate to hold the component fibrils together. These forces may or may not arise from covalent cross-links.
通过电子显微镜观察以及梭菌胶原酶溶解实验表明，老化人类肋软骨中的铁石棉样（石棉样）纤维具有胶原性质。这些纤维在尺寸、轮廓和排列上与真皮、滑膜、肌腱、纤维软骨和透明关节软骨中的胶原在形态上有所不同。它们的宽度可达1微米，周期长度为560至620埃。其厚度、笔直度和平行排列表明铁石棉样纤维是刚性的。面对制备技术时它们的稳定性表明，是内聚力而非通过基质耗尽产生的空间并置作用将组成原纤维聚集在一起。这些力可能来自也可能不来自共价交联。
