色甘酸对大鼠腹膜肥大细胞过敏性组胺释放的影响。
Effect of cromoglycate on anaphylactic histamine release from rat peritoneal mast cells.
作者信息
Garland L G
出版信息
Br J Pharmacol. 1973 Sep;49(1):128-30. doi: 10.1111/j.1476-5381.1973.tb08275.x.
Abstract
Cromoglycate (1-30 muM) produced a concentration-dependent inhibition of anaphylactic histamine release from actively sensitized rat peritoneal mast cells but at lower concentrations (0.01-0.1 muM) occasionally produced a concentration-dependent enhancement of histamine release.
摘要
色甘酸（1 - 30微摩尔）对主动致敏的大鼠腹膜肥大细胞释放过敏反应性组胺产生浓度依赖性抑制作用，但在较低浓度（0.01 - 0.1微摩尔）时，偶尔会产生浓度依赖性的组胺释放增强作用。
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本文引用的文献
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Anaphylaxis in chopped guinea pig lung. II. Enhancement of the anaphylactic release of histamine and slow reacting substance by certain dibasic aliphatic acids and inhibition by monobasic fatty acids.豚鼠肺切碎物中的过敏反应。II. 某些二元脂肪酸对组胺和慢反应物质过敏释放的增强作用以及一元脂肪酸的抑制作用
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Inhibition of allergic reactions in man and other species by cromoglycate.色甘酸盐对人和其他物种过敏反应的抑制作用。
Int Arch Allergy Appl Immunol. 1970;38(1):68-77. doi: 10.1159/000230260.
4
Biologic properties of rat antibodies. 3. Histamine release mediated by two classes of antibodies.大鼠抗体的生物学特性。3. 两类抗体介导的组胺释放
J Immunol. 1969 Feb;102(2):327-37.
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Pulmonary infiltrates with eosinophilia in an asthmatic patient treated with disodium cromoglycate.接受色甘酸钠治疗的哮喘患者出现伴有嗜酸性粒细胞增多的肺部浸润。
Lancet. 1972 Nov 11;2(7785):1032. doi: 10.1016/s0140-6736(72)92446-4.
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Disodium cromoglycate (Intal).色甘酸钠（因他舒）。
Adv Drug Res. 1970;5:115-96.
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