大鼠肛门尾骨肌中可卡因和6-羟基多巴胺诱导的对羟甲唑啉超敏反应的缺失。
The absence of cocaine- and 6-hydroxydopamine-induced supersensitivity to oxymetazoline in the rat anococcygeus muscle.
作者信息
Gibson A, Pollock D
出版信息
Br J Pharmacol. 1973 Dec;49(4):726-7. doi: 10.1111/j.1476-5381.1973.tb08556.x.
Abstract
Neither cocaine nor 6-hydroxydopamine potentiated the responses of the anococcygeus muscl_ to oxymetazoline, suggesting that the specific supersensitivity to noradrenaline produced by these drugs is due to abolition of neuronal uptake mechanisms.
摘要
可卡因和6-羟基多巴胺均未增强肛门尾骨肌对羟甲唑啉的反应，这表明这些药物所产生的对去甲肾上腺素的特异性超敏反应是由于神经元摄取机制的消除。
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