Mak T W, Aye M T, Messner H, Sheinin R, Till J E, McCulloch E A
Br J Cancer. 1974 Jun;29(6):433-7. doi: 10.1038/bjc.1974.95.
An enzyme activity with the characteristics of reverse transcriptase was detected in marrow from patients with leukaemia in relapse and in firm haematological remission. The endogenous enzyme activities increased following culture, and in remission patients the enzyme activities reached levels equal to or exceeding those found in relapse.
在复发期白血病患者以及血液学缓解稳定期患者的骨髓中检测到了具有逆转录酶特征的酶活性。内源性酶活性在培养后增加,并且在缓解期患者中,酶活性达到或超过复发期患者的水平。