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1
Reverse transcriptase activity: increase in marrow cultures from leukaemic patients in relapse and remission.逆转录酶活性：白血病复发和缓解患者骨髓培养物中的活性增加。
Br J Cancer. 1974 Jun;29(6):433-7. doi: 10.1038/bjc.1974.95.
2
Particles with characteristics of leukoviruses in cultures of marrow cells from leukemic patients in remission and relapse.来自缓解期和复发期白血病患者骨髓细胞培养物中具有白血病病毒特征的颗粒。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4336-40. doi: 10.1073/pnas.71.11.4336.
3
[Reverse transcriptase activities in human leukemia (author's transl)].人类白血病中的逆转录酶活性（作者译）
Rinsho Ketsueki. 1982 Feb;23(2):155-62.
4
Human leukaemic cells contain reverse transcriptase associated with a high molecular weight virus-related RNA.人类白血病细胞含有与高分子量病毒相关RNA结合的逆转录酶。
Nat New Biol. 1972 Nov 15;240(98):72-5. doi: 10.1038/newbio240072a0.
5
Biochemical properties of reverse transcriptase activities from human cells and RNA tumor viruses.来自人类细胞和RNA肿瘤病毒的逆转录酶活性的生化特性。
Johns Hopkins Med J Suppl. 1973;2:180-92.
6
DNA polymerases in normal and leukemic human hematopoietic cells.正常和白血病人类造血细胞中的DNA聚合酶。
Blood. 1974 Jul;44(1):19-32.
7
Autoradiographic studies of RNA metabolism in human leukaemic blast cells.人白血病原始细胞中RNA代谢的放射自显影研究。
Acta Haematol. 1971;45(1):17-22. doi: 10.1159/000208602.
8
[Lactate dehydrogenase in human leukemia. A clinico-experimental study].[人类白血病中的乳酸脱氢酶。一项临床实验研究]
Verh K Vlaam Acad Geneeskd Belg. 1972;34(5-6):587-732.
9
[Serum and urine muramidase activity in acute and chronic leukemia].[急性和慢性白血病患者血清及尿液中溶菌酶活性]
Schweiz Med Wochenschr. 1970 Nov 14;100(46):1993-5.
10
Reverse transcriptase in leukocytes of leukemic patients in remission.缓解期白血病患者白细胞中的逆转录酶。
N Engl J Med. 1976 Jan 8;294(2):75-80. doi: 10.1056/NEJM197601082940203.

引用本文的文献

1
Particles with characteristics of leukoviruses in cultures of marrow cells from leukemic patients in remission and relapse.来自缓解期和复发期白血病患者骨髓细胞培养物中具有白血病病毒特征的颗粒。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4336-40. doi: 10.1073/pnas.71.11.4336.
2
Antibodies in human sera to oncorna virus-like proteins from normal or leukemia marrow cell cultures.人血清中针对来自正常或白血病骨髓细胞培养物的肿瘤RNA病毒样蛋白的抗体。
J Exp Med. 1976 Nov 2;144(5):1243-53. doi: 10.1084/jem.144.5.1243.
3
Viral-related information in oncornavirus-lik particles isolated from cultures of marrow cells from leukemic patients in relapse and remission.从复发和缓解期白血病患者骨髓细胞培养物中分离出的类肿瘤病毒颗粒中的病毒相关信息。
Proc Natl Acad Sci U S A. 1975 Feb;72(2):623-7. doi: 10.1073/pnas.72.2.623.
4
Oncornavirus-like particles from cultured bone marrow cells preceding leukemia and malignant histiocytosis.白血病和恶性组织细胞增多症发生前培养骨髓细胞中类肿瘤病毒样颗粒。
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2804-8. doi: 10.1073/pnas.72.7.2804.

本文引用的文献

1
Colony formation by normal and leukemic human marrow cells in culture: effect of conditioned medium from human leukocytes.培养条件下人正常和白血病骨髓细胞的集落形成：人白细胞条件培养基的作用
Blood. 1971 Jan;37(1):1-5.
2
RNA dependent DNA polymerase of human acute leukaemic cells.人类急性白血病细胞的RNA依赖性DNA聚合酶
Nature. 1970 Dec 5;228(5275):927-9. doi: 10.1038/228927a0.
3
The influence of morphology on prognosis in acute leukemia.形态学对急性白血病预后的影响。
Can Med Assoc J. 1967 Jun 24;96(25):1610-4.
4
Growth of leukemic cells in culture.白血病细胞在培养中的生长。
Blood. 1972 Dec;40(6):806-11.
5
Terminal deoxynucleotidyl transferase in a case of childhood acute lymphoblastic leukemia.儿童急性淋巴细胞白血病一例中的末端脱氧核苷酸转移酶
Proc Natl Acad Sci U S A. 1973 Feb;70(2):521-5. doi: 10.1073/pnas.70.2.521.
6
Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses.致癌RNA病毒中DNA指导的DNA聚合酶产物的特性分析
Nature. 1970 Aug 8;227(5258):563-7. doi: 10.1038/227563a0.
7
Human leukaemic cells contain reverse transcriptase associated with a high molecular weight virus-related RNA.人类白血病细胞含有与高分子量病毒相关RNA结合的逆转录酶。
Nat New Biol. 1972 Nov 15;240(98):72-5. doi: 10.1038/newbio240072a0.
8
Reverse transcriptase activity of human acute leukaemic cells: purification of the enzyme, response to AMV 70S RNA, and characterization of the DNA product.人急性白血病细胞的逆转录酶活性：酶的纯化、对禽成髓细胞瘤病毒70S RNA的反应以及DNA产物的特性分析
Nat New Biol. 1972 Nov 15;240(98):67-72. doi: 10.1038/newbio240067a0.
9
Stimulated normal human lymphocytes contain a ribonuclease-sensitive DNA polymerase distinct from viral RNA-directed DNA polymerase.受刺激的正常人淋巴细胞含有一种对核糖核酸酶敏感的DNA聚合酶，它不同于病毒RNA指导的DNA聚合酶。
Proc Natl Acad Sci U S A. 1972 Nov;69(11):3228-32. doi: 10.1073/pnas.69.11.3228.

逆转录酶活性：白血病复发和缓解患者骨髓培养物中的活性增加。

Reverse transcriptase activity: increase in marrow cultures from leukaemic patients in relapse and remission.

作者信息

Mak T W, Aye M T, Messner H, Sheinin R, Till J E, McCulloch E A

出版信息

Br J Cancer. 1974 Jun;29(6):433-7. doi: 10.1038/bjc.1974.95.

DOI:10.1038/bjc.1974.95
PMID:4137170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2009110/
Abstract

An enzyme activity with the characteristics of reverse transcriptase was detected in marrow from patients with leukaemia in relapse and in firm haematological remission. The endogenous enzyme activities increased following culture, and in remission patients the enzyme activities reached levels equal to or exceeding those found in relapse.

摘要

在复发期白血病患者以及血液学缓解稳定期患者的骨髓中检测到了具有逆转录酶特征的酶活性。内源性酶活性在培养后增加，并且在缓解期患者中，酶活性达到或超过复发期患者的水平。