形态学对急性白血病预后的影响。
The influence of morphology on prognosis in acute leukemia.
作者信息
Hasselback R, Curtis J, Soots M, Robertson G L, Cowan D H, Hart G D
出版信息
Can Med Assoc J. 1967 Jun 24;96(25):1610-4.
The presence of definite cytoplasmic granulation in at least some of the malignant cells was used as the sole criterion to separate 156 patients with acute leukemia into two groups: 110 with myeloblastic (AML), and 46 with lymphoblastic or stem cell leukemia (ALL). The median survival from the onset of symptoms in patients with AML was 20 weeks, and those with ALL 37 weeks. The difference in survival in these two groups is much greater for patients under the age of 25 than for those over the age of 25.
至少部分恶性细胞中存在明确的细胞质颗粒，以此为唯一标准，将156例急性白血病患者分为两组：110例为粒细胞白血病（AML），46例为淋巴细胞或干细胞白血病（ALL）。AML患者从症状出现开始的中位生存期为20周，ALL患者为37周。25岁以下患者这两组的生存期差异比25岁以上患者大得多。
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