人脑与人类T细胞系之间的共同抗原决定簇。
Shared antigenic determinants between human brain and human T-cell line.
作者信息
Takada A, Takada Y, Ito U, Minowada J
出版信息
Clin Exp Immunol. 1974 Dec;18(4):491-8.
Abstract
Rabbits were immunized with MOLT cells (T cells) and RPMI number 1788 (B cells) to get respective antisera. These sera were absorbed with human liver, human brain, or various B cells (RPMI number 1788, SOMMER-B cell, B-35M cells and B-411 cells). The results indicate that the cytotoxicity of rabbit anti-MOLT serum against MOLT cells could be absorbed to some extent with human liver and various B cells but not completely. Human brain could completely absorb anti-MOLT activity from rabbit anti-MOLT serum. Human brain could not remove anti-B-cell activity from rabbit anti-RPMI number 1788 (B cells). Rat brain did not remove anti-MOLT activity from anti-MOLT serum. These data suggest that human brain has antigenic determinants identical or very similar to those found on MOLT cells and thus possibly human thymocytes.
摘要
用毛细胞白血病细胞（T细胞）和RPMI 1788细胞（B细胞）免疫兔子，以获得相应的抗血清。这些血清用人肝、人脑或各种B细胞（RPMI 1788细胞、索默B细胞、B - 35M细胞和B - 411细胞）吸收。结果表明，兔抗毛细胞白血病血清对毛细胞白血病细胞的细胞毒性可被人肝和各种B细胞部分吸收，但不能完全吸收。人脑可完全从兔抗毛细胞白血病血清中吸收抗毛细胞白血病活性。人脑不能从兔抗RPMI 1788（B细胞）血清中去除抗B细胞活性。大鼠脑不能从抗毛细胞白血病血清中去除抗毛细胞白血病活性。这些数据表明，人脑具有与毛细胞白血病细胞上发现的抗原决定簇相同或非常相似的抗原决定簇，因此可能与人胸腺细胞的抗原决定簇相同或非常相似。
相似文献
1
Shared antigenic determinants between human brain and human T-cell line.人脑与人类T细胞系之间的共同抗原决定簇。
Clin Exp Immunol. 1974 Dec;18(4):491-8.
2
Antigenic determinants common to established human B-cell lines, but not shared by human T-cell lines (molt and sommer).已建立的人B细胞系共有的抗原决定簇，但人T细胞系（莫尔特和索默）不共享。
Clin Exp Immunol. 1975 Aug;21(2):267-77.
3
Human T lymphocytes and myeloid colony forming cells share common antigen.人类T淋巴细胞和髓系集落形成细胞具有共同抗原。
Exp Hematol. 1980 Jan;8(1):6-15.
4
Analysis of the antigenic structure of the thymocyte surface membrane by heterologous anti-thymocyte serum.用异种抗胸腺细胞血清分析胸腺细胞表面膜的抗原结构。
Eur J Immunol. 1977 Mar;7(3):131-6. doi: 10.1002/eji.1830070304.
5
Antigenic correlations between brain and thymus. III. Reciprocal blocking of antigenic determinants on mouse brain and thymocytes by anti-mouse-brain- and anti-thy-1.2 sera.脑与胸腺之间的抗原相关性。III. 抗小鼠脑血清和抗Thy-1.2血清对小鼠脑和胸腺细胞上抗原决定簇的相互封闭作用
Z Immunitatsforsch Exp Klin Immunol. 1974 Feb;146(4):360-9.
6
[Preparation and serological properties of immune sera chiefly specific to the T- or B-lymphocytes of dogs].[主要针对犬T淋巴细胞或B淋巴细胞的免疫血清的制备及血清学特性]
Fiziol Zh (1978). 1980 Sep-Oct;26(5):618-21.
7
8
9
Analysis of some in vitro activities of rabbit and duck anti-chicken anti-brain sera.兔和鸭抗鸡抗脑血清的一些体外活性分析。
Folia Biol (Praha). 1974;20(6):386-91.
10
Human B-lymphocyte heteroantigens: direct evidence for specificities not shared by monocytes.人类B淋巴细胞异种抗原：单核细胞不共享特异性的直接证据。
Clin Exp Immunol. 1978 Dec;34(3):379-87.
引用本文的文献
1
Antibodies to brain tissue in sera of schizophrenic patients--preliminary findings.精神分裂症患者血清中脑组织抗体——初步研究结果
Eur Arch Psychiatry Clin Neurosci. 1993;242(5):314-7. doi: 10.1007/BF02190392.
2
Immunobiologic aspects of the brain and human gliomas. A review.大脑与人类胶质瘤的免疫生物学方面。综述
Am J Pathol. 1980 Feb;98(2):517-68.
3
Lack of expression on cultured human T-lymphocytes of a T-cell antigen shared by the MOLT-4 cell line and normal human thymocytes.MOLT-4细胞系和正常人胸腺细胞共有的一种T细胞抗原在培养的人T淋巴细胞上缺乏表达。
In Vitro. 1980 Sep;16(9):754-60. doi: 10.1007/BF02619309.
4
Human glioma associated and related antigens, identified by monoclonal antibodies.通过单克隆抗体鉴定的人胶质瘤相关抗原
Neurosurg Rev. 1984;7(1):23-8. doi: 10.1007/BF01743287.
5
Shared antigenic determinants between brain and thymus-derived lymphocytes in dogs.犬脑源性淋巴细胞和胸腺源性淋巴细胞之间的共同抗原决定簇。
Acta Neuropathol. 1981;54(1):75-82. doi: 10.1007/BF00691334.
6
Immunohistochemical recognition of human neuroepithelial tumors by anti-Leu 7 (HNK-1) monoclonal antibody.抗Leu 7（HNK-1）单克隆抗体对人神经上皮肿瘤的免疫组织化学识别
Acta Neuropathol. 1986;69(3-4):227-33. doi: 10.1007/BF00688298.
7
Shared antigenic determinants between human hemopoietic cells and nervous tissues and tumors.人类造血细胞、神经组织和肿瘤之间的共同抗原决定簇。
Acta Neuropathol. 1985;67(1-2):58-66. doi: 10.1007/BF00688124.
8
Detection of measles virus antigen(s) in peripheral lymphocytes from patients with subacute sclerosing panencephalitis.亚急性硬化性全脑炎患者外周淋巴细胞中麻疹病毒抗原的检测
Arch Virol. 1979;60(3-4):291-7. doi: 10.1007/BF01317500.
9
Reactivity of anti-human brain serum with human lymphocytes.抗人脑血清与人类淋巴细胞的反应性。
Am J Pathol. 1977 Jan;86(1):1-16.
10
Rabbit antiserum to human thymocyte membranes: specificity for normal and malignant T-lymphocytes.抗人胸腺细胞膜兔抗血清：对正常和恶性T淋巴细胞的特异性
Clin Exp Immunol. 1978 Aug;33(2):283-91.
本文引用的文献
1
THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES.AKR胸腺抗原及其在白血病和神经组织中的分布。
J Exp Med. 1964 Sep 1;120(3):413-33. doi: 10.1084/jem.120.3.413.
2
Culture of normal human leukocytes.正常人白细胞培养。
JAMA. 1967 Feb 20;199(8):519-24.
3
Selective gene action in the specification of cell surface structure.细胞表面结构特化中的选择性基因作用。
Am J Pathol. 1971 Nov;65(2):439-50.
4
Surface-bound immunoglobulin as a marker of B lymphocytes in man.表面结合免疫球蛋白作为人类B淋巴细胞的标志物。
Nat New Biol. 1971 Dec 22;234(51):251-2. doi: 10.1038/newbio234251a0.
5
Binding of sheep red blood cells to a large population of human lymphocytes.绵羊红细胞与大量人类淋巴细胞的结合。
Nature. 1971 Apr 23;230(5295):531-2. doi: 10.1038/230531a0.
6
Tissue- and species-specific antibodies in antithymocyte globulin.抗胸腺细胞球蛋白中的组织和物种特异性抗体。
Transplantation. 1972 Mar;13(3):306-9. doi: 10.1097/00007890-197203000-00017.
7
Thymus-specific antigens on human thymocytes and on thymic-derived lymphocytes.人类胸腺细胞和胸腺来源淋巴细胞上的胸腺特异性抗原。
Transplantation. 1973 Apr;15(4):415-7. doi: 10.1097/00007890-197304000-00014.
8
Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes.形成玫瑰花结的人淋巴细胞系。I. 胸腺衍生淋巴细胞起源的建立及证据。
J Natl Cancer Inst. 1972 Sep;49(3):891-5.
9
Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines.人类白血病细胞和人类淋巴母细胞系上补体和免疫球蛋白的受体
J Clin Invest. 1972 Aug;51(8):1933-8. doi: 10.1172/JCI106999.
10
Brain-associated theta antigen: reactivity of rabbit anti-mouse brain with mouse lymphoid cells.脑相关θ抗原：兔抗小鼠脑与小鼠淋巴细胞的反应性。
Cell Immunol. 1971 Aug;2(4):353-61. doi: 10.1016/0008-8749(71)90070-0.
Zotero 插件