一株谷氨酰胺转移核糖核酸合成酶发生改变的温度敏感型大肠杆菌突变体的分离与部分特性分析
Isolation and partial characterization of a temperature-sensitive Escherichia coli mutant with altered glutaminyl-transfer ribonucleic acid synthetase.
作者信息
Körner A, Magee B B, Liska B, Low K B, Adelberg E A, Söll D
出版信息
J Bacteriol. 1974 Oct;120(1):154-8. doi: 10.1128/jb.120.1.154-158.1974.
Abstract
A temperature-sensitive mutant of Escherichia coli has been found in which the conditional growth is a result of a thermosensitive glutaminyl-transfer ribonucleic acid synthetase. The corresponding genetic locus glnS is cotransduced with lip. In a strain containing the mutationally altered glutaminyl-transfer ribonucleic acid synthetase, no derepression of the enzyme itself nor of glutamine synthetase was observed.
摘要
已发现大肠杆菌的一种温度敏感突变体，其条件生长是由热敏谷氨酰胺转移核糖核酸合成酶导致的。相应的基因位点glnS与lip共转导。在含有经突变改变的谷氨酰胺转移核糖核酸合成酶的菌株中，未观察到该酶本身或谷氨酰胺合成酶的去阻遏现象。
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Isolation and partial characterization of a temperature-sensitive Escherichia coli mutant with altered glutaminyl-transfer ribonucleic acid synthetase.一株谷氨酰胺转移核糖核酸合成酶发生改变的温度敏感型大肠杆菌突变体的分离与部分特性分析
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引用本文的文献
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Response of Escherichia coli auxotrophs to heat after treatment with mutagenic alkyl methanesulfonates.诱变剂甲磺酸烷基酯处理后大肠杆菌营养缺陷型对热的反应
J Bacteriol. 1962 Feb;83(2):241-9. doi: 10.1128/jb.83.2.241-249.1962.
3
Genetic variation in the sex factor of Escherichia coli.大肠杆菌性别因子的遗传变异。
J Bacteriol. 1960 Mar;79(3):321-30. doi: 10.1128/jb.79.3.321-330.1960.
4
Hybridization between Escherichia coli and Shigella.大肠杆菌与志贺氏菌之间的杂交。
J Bacteriol. 1957 Oct;74(4):461-76. doi: 10.1128/jb.74.4.461-476.1957.
5
Isolation and partial characterization of temperature-sensitive Escherichia coli mutants with altered leucyl- and seryl-transfer ribonucleic acid synthetases.具有改变的亮氨酰和丝氨酰转移核糖核酸合成酶的温度敏感型大肠杆菌突变体的分离及部分特性研究
J Bacteriol. 1971 Nov;108(2):742-50. doi: 10.1128/jb.108.2.742-750.1971.
6
Molecular weighr of Escherichia coli glutaminyl transfer ribonucleic acid synthetase, and isolation of its complex with glutamine transfer ribonucleic acid.大肠杆菌谷氨酰胺转移核糖核酸合成酶的分子量及其与谷氨酰胺转移核糖核酸复合物的分离。
Biochemistry. 1971 Apr 27;10(9):1728-32. doi: 10.1021/bi00785a034.
7
Biochemical and genetic studies with lysine+methionine mutants of Escherichia coli: lipoic acid and alpha-ketoglutarate dehydrogenase-less mutants.大肠杆菌赖氨酸 + 蛋氨酸突变体的生化与遗传学研究：硫辛酸和α-酮戊二酸脱氢酶缺失突变体
J Gen Microbiol. 1968 Oct;53(3):363-81. doi: 10.1099/00221287-53-3-363.
8
Isolation and mapping of polynucleotide phosphorylase mutants of Escherichia coli.大肠杆菌多核苷酸磷酸化酶突变体的分离与定位
J Bacteriol. 1969 Mar;97(3):1431-6. doi: 10.1128/jb.97.3.1431-1436.1969.
9
Thermosensitive mutants of Escherichia coli unable to propagate RNA phage at 42 degrees C and altered in protein synthesis.大肠杆菌的热敏突变体在42摄氏度时无法繁殖RNA噬菌体且蛋白质合成发生改变。
Eur J Biochem. 1974 Apr 16;43(3):583-90. doi: 10.1111/j.1432-1033.1974.tb03445.x.
10
Isolation and characterization of a regulatory mutant of an aminoacyl-transfer ribonucleic acid synthetase in Escherichia coli K-12.大肠杆菌K-12中氨酰基转移核糖核酸合成酶调节突变体的分离与鉴定。
J Bacteriol. 1973 Mar;113(3):1096-103. doi: 10.1128/jb.113.3.1096-1103.1973.
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