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氨基糖苷类与粪便的结合。

Binding of aminoglycosides to feces.

作者信息

Wagman G H, Bailey J V, Weinstein M J

出版信息

Antimicrob Agents Chemother. 1974 Oct;6(4):415-7. doi: 10.1128/AAC.6.4.415.

Abstract

Gentamicin and several other basic antibiotics were examined for their ability to adsorb to dog feces. It was found that 44 to 90% of all antibiotics studied were adsorbed to feces depending on the ratio of antibiotic to fecal material. Attempts to extract these antibiotics by acid treatment after adsorption onto feces were only partially successful since large portions of the bound materials were not removed.

摘要

对庆大霉素和其他几种碱性抗生素吸附狗粪便的能力进行了研究。结果发现,根据抗生素与粪便物质的比例,所研究的所有抗生素中有44%至90%会被粪便吸附。粪便吸附抗生素后,通过酸处理来提取这些抗生素的尝试仅取得了部分成功,因为大部分结合物质并未被去除。

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Binding of aminoglycosides to feces.氨基糖苷类与粪便的结合。
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Structural origins of gentamicin antibiotic action.庆大霉素抗生素作用的结构起源
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