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直肠中含粘蛋白的组织细胞（粘蛋白吞噬细胞）

Mucoprotein-containing histiocytes (muciphages) in the rectum.

作者信息

Azzopardi J G, Evans D J

出版信息

J Clin Pathol. 1966 Jul;19(4):368-74. doi: 10.1136/jcp.19.4.368.

DOI:10.1136/jcp.19.4.368
PMID:4162901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473286/
Abstract

Mucoprotein-containing macrophages (muciphages) are a common finding in routine rectal biopsies, occurring in about 50% of cases. No correlation was found between their presence and the sex, age, and disease of the patient. They must be distinguished from the cells of Whipple's disease and from lipofuscin-containing macrophages. The origin of the mucoprotein is discussed and rectal epithelial mucin is considered a possible source.

摘要

含粘蛋白的巨噬细胞（粘蛋白巨噬细胞）在常规直肠活检中很常见，约50%的病例中会出现。未发现它们的存在与患者的性别、年龄和疾病之间存在相关性。必须将它们与惠普尔病的细胞以及含脂褐素的巨噬细胞区分开来。文中讨论了粘蛋白的来源，并认为直肠上皮粘蛋白是一种可能的来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/f5382e32300d/jclinpath00363-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/1286fe95eb6f/jclinpath00363-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/5d63ffd97f2f/jclinpath00363-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/24a0a9f3cb8d/jclinpath00363-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/5c527509a9b9/jclinpath00363-0067-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/374662eb654c/jclinpath00363-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/1f4d10161219/jclinpath00363-0068-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/d7504f08ca4a/jclinpath00363-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/f5382e32300d/jclinpath00363-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/1286fe95eb6f/jclinpath00363-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/5d63ffd97f2f/jclinpath00363-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/24a0a9f3cb8d/jclinpath00363-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/5c527509a9b9/jclinpath00363-0067-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/374662eb654c/jclinpath00363-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/1f4d10161219/jclinpath00363-0068-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/d7504f08ca4a/jclinpath00363-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3337/473286/f5382e32300d/jclinpath00363-0070-b.jpg

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1
Mucoprotein-containing histiocytes (muciphages) in the rectum.直肠中含粘蛋白的组织细胞（粘蛋白吞噬细胞）
J Clin Pathol. 1966 Jul;19(4):368-74. doi: 10.1136/jcp.19.4.368.
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[Catabolic processes in the rectal mucosa. Light and electron microscopic studies].[直肠黏膜中的分解代谢过程。光镜和电镜研究]
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本文引用的文献

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CEROID-LIKE COLONIC HISTIOCYTOSIS.类蜡样结肠组织细胞增多症
Am J Clin Pathol. 1964 Dec;42:581-93.
2
INTRA-ALVEOLAR MUCUS--REMOVAL BY MACROPHAGES: WITH IRON ACCUMULATION.
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GRANULAR CELLS AND GRANULAR CELL LESIONS.
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AMYLOIDOSIS IN RHEUMATOID ARTHRITIS INVESTIGATED BY MEANS OF RECTAL BIOPSY.
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4
Selective uptake of intraluminal dextran sulfate sodium and senna by macrophages in the cecal mucosa of the guinea pig.豚鼠盲肠黏膜中巨噬细胞对腔内硫酸葡聚糖钠和番泻叶的选择性摄取。
J Gastroenterol. 1996 Apr;31(2):189-98. doi: 10.1007/BF02389517.
5
Whipple's disease in the rectum. Light and electron microscopic findings.直肠惠普尔病。光镜和电镜检查结果。
Am J Pathol. 1968 Jun;52(6):1191-206.
6
Immunocytochemistry in the diagnosis of Whipple's disease.免疫细胞化学在惠普尔病诊断中的应用
J Clin Pathol. 1985 Apr;38(4):372-4. doi: 10.1136/jcp.38.4.372.
通过直肠活检对类风湿关节炎中的淀粉样变性进行研究。
Ann Rheum Dis. 1963 Jul;22(4):256-62. doi: 10.1136/ard.22.4.256.
5
Diagnosis of Whipple's disease by rectal biopsy.通过直肠活检诊断惠普尔病。
N Engl J Med. 1962 Jul 5;267:33-4. doi: 10.1056/NEJM196207052670108.