丘疹性黏蛋白病（黏液性水肿性苔藓）中一种独特诊断性血清球蛋白的研究。

James K, Fudenberg H, Epstein W L, Shuster J

Clin Exp Immunol. 1967 Mar;2(2):153-66.

An abnormal γ-globulin present in the sera of five patients with papular mucinosis (PM) (lichen myxedematosus) appears to be characteristic of the disease. The PM protein is closely related to myeloma paraproteins in that it is homogeneous in electrophoretic mobility and homogeneous with respect to light chain antigenic groups. The consistently basic nature of the abnormal γ-globulin was shown by various electrophoretic techniques. In contrast to myeloma paraproteins, the light chains of all five of the PM proteins are L in type. The above characteristics of the PM γ-globulin and the benign clinical course differentiate papular mucinosis from multiple myeloma with cutaneous involvement.

在五例丘疹性黏蛋白病（PM）（黏液性水肿性苔藓）患者血清中出现的一种异常γ球蛋白似乎是该疾病的特征。PM蛋白与骨髓瘤副蛋白密切相关，因为它在电泳迁移率上是均一的，并且在轻链抗原组方面也是均一的。通过各种电泳技术表明异常γ球蛋白始终具有碱性性质。与骨髓瘤副蛋白相反，所有五种PM蛋白的轻链均为L型。PMγ球蛋白的上述特征以及良性临床过程将丘疹性黏蛋白病与伴有皮肤受累的多发性骨髓瘤区分开来。