[乙肝表面抗原（HBs Ag）亚型的遗传传递（常染色体隐性）假说。凯尔·库默的例子]
[The hypothesis of the genetic transmission (autosomal recessive) of subtypes of HBs Ag. The example of Kel Kummer].
作者信息
Chaventré A
出版信息
C R Acad Hebd Seances Acad Sci D. 1978 Jan;286(1):133-6.
PMID:417847
Abstract
In a study of asymtomatic carriers of hepatitis B surface antigen (HBs Ag) in a closed population, the Twareg Kel Kummer, 18% of the population (79 individuals out of 439 tested) were found to be carriers of one of the 3 sub types: HBs Ag/a2 1 dw, HBs Ag/a2 1 yw and HBs Ag/a3 yw. Evidence from genealogies and the distribution of carriers in the pyramid of ages strongly supports the hypothesis of genetic transmission of the gene sub type as an autosomal recessive.
摘要
在对一个封闭人群中乙型肝炎表面抗原（HBs Ag）无症状携带者的研究中，对图阿雷格族凯尔库默人进行检测，发现该人群中有18%（439人中的79人）是三种亚型之一的携带者：HBs Ag/a2 1 dw、HBs Ag/a2 1 yw和HBs Ag/a3 yw。系谱证据以及携带者在年龄金字塔中的分布有力地支持了基因亚型作为常染色体隐性基因进行遗传传递的假说。
Zotero 插件