Houba V, Brown K N, Allison A C
Clin Exp Immunol. 1969 Jan;4(1):113-23.
Monkeys () were infected with different strains of and . The titres of non-sensitized sheep cell agglutinins (NSCAT), M-antiglobulins (rheumatoid factor-like globulins) and the levels of immunoglobulins (IgG, IgA and IgM) were determined in sera before and during the course of infections controlled by treatment with Suramin. Persistently high titres of NSCAT-agglutinins developed in monkeys infected with all three organisms. IgM levels increased in all animals reaching levels more than ten times the original values. The levels of IgA remained unchanged and of IgG slightly increased in some animals. Slightly elevated M-antiglobulin titres were occasionally found without any relation to the progress of infection. NSCAT-agglutinins were found to be macroglobulins (Sephadex G-200 immunoelectrophoresis, = 18·5) sensitive to β-mercaptoethanol treatment. Their activity was absorbed by sheep red blood cells, guinea-pig kidney cells and antigen.
猴子感染了不同菌株的[具体病原体名称缺失]和[具体病原体名称缺失]。在用苏拉明治疗控制感染的过程中，测定了感染前和感染期间血清中未致敏绵羊细胞凝集素（NSCAT）、M抗球蛋白（类风湿因子样球蛋白）的滴度以及免疫球蛋白（IgG、IgA和IgM）的水平。感染所有三种病原体的猴子体内持续出现高滴度的NSCAT凝集素。所有动物的IgM水平均升高，达到原值的十倍以上。IgA水平保持不变，部分动物的IgG水平略有升高。偶尔发现M抗球蛋白滴度略有升高，与感染进程无关。发现NSCAT凝集素是对β-巯基乙醇处理敏感的巨球蛋白（Sephadex G-200免疫电泳， = 18·5）。它们的活性被绵羊红细胞、豚鼠肾细胞和[具体抗原名称缺失]抗原吸收。
