抗原受体分子：抗κ轻链抗血清的抑制作用
Antigen receptor molecules: inhibition by antiserum against kappa light chains.
作者信息
Lesley J, Dutton R W
出版信息
Science. 1970 Jul 31;169(3944):487-8. doi: 10.1126/science.169.3944.487.
PMID:4193208
Abstract
Rabbit antiserum against mouse kappa chains, the predominant class of light chains found in mouse immunoglobulins, inhibits the immune response in vitro of mouse spleen cells to erythrocyte antigens. The inhibition becomes irreversible if the mouse spleen cells are treated briefly with both antiserum to kappa chains and complement.
摘要
针对小鼠κ链（小鼠免疫球蛋白中主要的轻链类别）的兔抗血清，可在体外抑制小鼠脾细胞对红细胞抗原的免疫反应。如果用κ链抗血清和补体对小鼠脾细胞进行短暂处理，这种抑制作用将变得不可逆。
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