Vissarionova V Ia, Bondarev G I, Stasenkova K P, Zemlianskaia T A
Vopr Pitan. 1979 Jan-Feb(1):36-40.
The effect of protein of isocaloric rations (10, 18 and 30 per cent of the total calorific value) differing in its proportion on the course of a subacute poisoning provoked by the acrylic acid nitrile (AAN) in a concentration of 9.7 +/- 2.8 mg/m3 was studied. A comparative study of the results obtained showed that a protein-rich ration produced a more pronounced protective effect. Against its background the AAN metabolites were eliminated from the organism more intensively. This effect could have been occasioned by an excessive supply to the organism together with the additional protein of free sulphur and of SH-group necessary for rendering the cyanides harmless. Considering the results obtained and with the view of a more effective prevention of the AAN poisoning it is advisable to recommend providing workers with a protein-rich medico-prophylactic ration containing an assortment of food products rich in sulphur-containing elements.
研究了等热量日粮（分别占总热量值的10%、18%和30%）中不同蛋白质比例对浓度为9.7±2.8mg/m³的丙烯腈（AAN）所致亚急性中毒病程的影响。对所得结果的比较研究表明，富含蛋白质的日粮具有更显著的保护作用。在此背景下，AAN代谢产物从机体中排出更为强烈。这种效应可能是由于随着额外蛋白质向机体过量供应了使氰化物无害化所需的游离硫和巯基。考虑到所得结果，并为了更有效地预防AAN中毒，建议为工人提供富含蛋白质的医疗预防日粮，其中包含各种富含含硫元素的食品。
