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兔脉络膜血流速度与眼压之间的关系。

Relationship between blood flow velocity in the choroid and intraocular pressure in rabbits.

作者信息

Takats I, Leiszter F

出版信息

Acta Ophthalmol (Copenh). 1979 Feb;57(1):48-54. doi: 10.1111/j.1755-3768.1979.tb06658.x.

DOI:10.1111/j.1755-3768.1979.tb06658.x
PMID:419976
Abstract

By using thermistors for calorimetry to monitor blood flow velocity in the choroid of the anaesthetized rabbit, it was found that an elevation of intraocular pressure reduced the choroidal blood flow. The relationship between the ratio of perfusion pressure to intraocular tension (x) and the reciprocal value of the percentage of blood flow velocity (l/y) showed a curve convex towards the pressure axis. On a log-lin scale the graph was linear. A significant linear correlation with a coefficient of 0.965 was obtained. The regression equation was found to be log l/y = 0.48x-1.98 +/- 0.29. From the present experiments it is concluded that the vascular bed of the choroid in the rabbit is a passive one with no sign of autoregulation. The observations are discussed from the point of view of blood supply and possible damage to the optic disc.

摘要

通过使用热敏电阻进行量热法来监测麻醉兔脉络膜中的血流速度,发现眼压升高会降低脉络膜血流。灌注压与眼内压之比(x)与血流速度百分比的倒数(1/y)之间的关系呈现出一条向压力轴凸出的曲线。在对数-线性尺度上,该图呈线性。获得了系数为0.965的显著线性相关性。回归方程为log l/y = 0.48x - 1.98 ± 0.29。从目前的实验得出结论,兔脉络膜的血管床是被动的,没有自动调节的迹象。从血液供应和对视盘可能的损伤角度对这些观察结果进行了讨论。

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