庆大霉素和韦达霉素的体外抗菌活性比较。
Comparison of in vitro antibacterial activities of gentamicin and verdamicin.
作者信息
Yu P K, Washington J A
出版信息
Antimicrob Agents Chemother. 1974 Oct;6(4):526-8. doi: 10.1128/AAC.6.4.526.
Abstract
The in vitro activities of verdamicin and gentamicin were studied in parallel against 1,049 bacterial isolates. Verdamicin demonstrated activity similar to that of gentamicin against members of the family Enterobacteriaceae and against Pseudomonas aeruginosa at 2 and 8 mug/ml, respectively. Proteus rettgeri and Providencia stuartii were notably more susceptible to verdamicin. The new aminoglycoside was also highly active against staphylococci but was not effective against group D streptococci.
摘要
对1049株细菌分离株同时研究了韦他霉素和庆大霉素的体外活性。韦他霉素在浓度分别为2微克/毫升和8微克/毫升时，对肠杆菌科菌属及铜绿假单胞菌显示出与庆大霉素相似的活性。雷氏变形杆菌和斯氏普罗威登斯菌对韦他霉素尤为敏感。这种新的氨基糖苷类药物对葡萄球菌也有很高活性，但对D组链球菌无效。
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