白色念珠菌生长阶段的抗原性与系统性念珠菌病诊断的相关性。
Relevance of antigenicity of Candida albicans growth phases to diagnosis of systemic candidiasis.
作者信息
Evans E G, Richardson M D, Odds F C, Holland K T
出版信息
Br Med J. 1973 Oct 13;4(5884):86-7. doi: 10.1136/bmj.4.5884.86.
Abstract
The antigenicity of the two growth phases of Candida albicans has been compared by using crossed immunoelectrophoresis and double-diffusion techniques. Qualitative and quantitative differences in antigenic composition between the phases have been revealed and moreover a specific mycelial antigenic component demonstrated.It is postulated that the use of specific mycelial antigens for routine diagnostic precipitin testing in patients with suspected systemic candidiasis would give more reliable results than at present obtained with yeast cell antigens.
摘要
通过交叉免疫电泳和双向扩散技术比较了白色念珠菌两个生长阶段的抗原性。已揭示出这两个阶段抗原组成的定性和定量差异，并且还证实了一种特定的菌丝体抗原成分。据推测，对于疑似系统性念珠菌病患者，使用特定的菌丝体抗原进行常规诊断沉淀试验将比目前使用酵母细胞抗原获得更可靠的结果。
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