反三碘甲状腺原氨酸与三碘甲状腺原氨酸比值及孕周

Reverse tri-iodothyronine to tri-iodothyronine ratio and gestational age.

作者信息

Isaac R M, Hayek A, Standefer J C, Eaton R P

出版信息

J Pediatr. 1979 Mar;94(3):477-9. doi: 10.1016/s0022-3476(79)80605-8.

Abstract

The biologic significance of reverse tri-iodothyronine is not yet identified. Cord blood values reflect the fetal thyroid state, with rT3 excess and tri-iodothyronine deficiency. In an attempt to correlate thyroid function and gestational age, T3 and rT3 concentrations were measured by radioimmunoassay on 64 cord blood samples. Infant gestational ages ranged from 29 to 42 weeks; birth weights from 650 to 3,870 gm. The results show a significant positive correlation between gestational age and T3 and a significant negative correlation between gestational age and rT3. The rT3/T3 offers the best correlation.

摘要

反式三碘甲状腺原氨酸的生物学意义尚未明确。脐血值反映胎儿甲状腺状态，存在反式三碘甲状腺原氨酸过量和三碘甲状腺原氨酸缺乏的情况。为了将甲状腺功能与孕周相关联，通过放射免疫分析法对64份脐血样本进行了三碘甲状腺原氨酸（T3）和反式三碘甲状腺原氨酸（rT3）浓度测定。婴儿孕周范围为29至42周；出生体重为650至3870克。结果显示孕周与T3之间存在显著正相关，孕周与rT3之间存在显著负相关。反式三碘甲状腺原氨酸与三碘甲状腺原氨酸的比值相关性最佳。