Paparella M M, Goycoolea M V, Meyerhoff W L, Shea D
Laryngoscope. 1979 Jan;89(1):43-58. doi: 10.1288/00005537-197901000-00005.
Clinical observation of patients with fluctuant sensorineural hearing loss following or occurring with chronic otitis media led to the hypothesis that endolymphatic hydrops can result from chronic otitis media. Illustrative case reports are described. This hypothesis resulted in a temporal bone study of 560 cases in which 109 temporal bones demonstrated the presence of hydrops and 194 evidenced otitis media. Seventy-five cases demonstrated both otitis media and hydrops, of which 20 cases were selected for more detailed histopathological study. An interesting finding was the presence of apical hydrops in every case of the latter group. Statistical interpretation of this data helped rule out a coincidental or chance occurrence. A discussion of this clinical relationship included the significance of subclinical (silent) otitis media as a possible cause of endolymphatic hydrops.
对慢性中耳炎后出现或伴发波动性感音神经性听力损失患者的临床观察，引发了内淋巴积水可由慢性中耳炎导致的假说。文中描述了典型病例报告。这一假说促使对560例颞骨进行研究，其中109块颞骨显示存在积水，194块有中耳炎证据。75例同时存在中耳炎和积水，其中20例被选作更详细的组织病理学研究。一个有趣的发现是后一组的每个病例均存在顶区积水。对该数据的统计学分析有助于排除偶然或巧合情况。对这种临床关系的讨论包括亚临床（隐匿性）中耳炎作为内淋巴积水可能病因的重要性。
