多环烃的诱变性。V. 体内姐妹染色单体交换的诱导
Mutagenicity of polycyclic hydrocarbons. V. Induction of sister-chromatid exchanges in vivo.
作者信息
Roszinsky-Köcher G, Basler A, Röhrborn G
出版信息
Mutat Res. 1979 Jan;66(1):65-7.
PMID:423906
Abstract
The potency of polycyclic hydrocarbons to induce SCEs in vivo was analysed. The most potent SCE-inducing compound was benzo[a]pyrene. Benzanthracene, benzo[b]fluoranthene, benzo[e]pyrene, phenanthrene, chrysene and dibenzanthracene enhanced the SCE frequency to a smaller extent. The number of anthracene-induced SCEs per metaphase was not increased as compared with the controls.
摘要
分析了多环烃在体内诱导姐妹染色单体交换（SCEs）的能力。最有效的SCE诱导化合物是苯并[a]芘。苯并蒽、苯并[b]荧蒽、苯并[e]芘、菲、 Chrysene和二苯并蒽在较小程度上提高了SCE频率。与对照组相比，每个中期蒽诱导的SCE数量没有增加。
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