Weiss R, Birch-Hirschfeld E, Zimmer C, Luck G
Nucleic Acids Res. 1979 Feb;6(2):757-66. doi: 10.1093/nar/6.2.757.
In studies of some sequence dependent structural factors and stabilizing effects of oligonucleotides the octanucleotide d(pG-A-T-C-T-T-T-T) was of particular interest in view of the presence of an endonuclease cleavage site. Its chemical synthesis is reported as well as the structural effects in CD spectral properties of the octanucleotide and of some related compounds.
在对某些寡核苷酸的序列依赖性结构因素和稳定作用的研究中,八聚体d(pG-A-T-C-T-T-T-T)由于存在一个核酸内切酶切割位点而特别受关注。本文报道了其化学合成方法以及该八聚体和一些相关化合物在圆二色光谱性质方面的结构效应。