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交叉神经支配后猫的快、慢肌中肌球蛋白的酶学特性

Enzymic properties of myosin in fast and slow twitch muscles of the cat following cross-innervation.

作者信息

Buller A J, Mommaerts W F, Seraydarian K

出版信息

J Physiol. 1969 Dec;205(3):581-97. doi: 10.1113/jphysiol.1969.sp008984.

Abstract
  1. Following cross-innervation of the cat flexor digitorum longus muscle (F.D.L., fast-twitch) and soleus muscle (slow-twitch) the isometric twitch speed of the F.D.L. muscle decreases while the contraction time of soleus increases. The tetanus-twitch ratio of soleus is also increased.2. Myosin or myofibrils from normal or self-reinnervated fast-twitch muscles of the cat split adenosine triphosphate (ATP) more rapidly than myosin or myofibrils from slow twitch muscles.3. Following cross-innervation the myosin and myofibrillar ATPase activity of flexor digitorum longus muscle falls, to become nearly equal to that of normal or self-reinnervated soleus muscle. The ATPase activity of cross-innervated soleus muscle increases only slightly.
摘要
  1. 对猫的趾长屈肌(F.D.L.,快肌)和比目鱼肌(慢肌)进行交叉神经支配后,F.D.L. 肌的等长收缩速度降低,而比目鱼肌的收缩时间增加。比目鱼肌的强直收缩与单收缩比值也增加。

  2. 来自猫正常或自身再支配的快肌的肌球蛋白或肌原纤维比来自慢肌的肌球蛋白或肌原纤维更快速地分解三磷酸腺苷(ATP)。

  3. 交叉神经支配后,趾长屈肌的肌球蛋白和肌原纤维ATP酶活性下降,几乎与正常或自身再支配的比目鱼肌的活性相等。交叉神经支配的比目鱼肌的ATP酶活性仅略有增加。

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