小马对甲型马流感病毒2型的反应。I. 接触后的血清和鼻抗体滴度
The response of ponies to Myxovirus influenzae A-equi 2. I. Serum and nasal antibody titres following exposure.
作者信息
Rouse B T, Ditchfield W J
出版信息
Can J Comp Med. 1970 Jan;34(1):1-5.
The antibody response in serum and nasal secretions of groups of ponies vaccinated or infected with Myxovirus influenzae A-equi 2 was examined. Following infection by aerosol with live virus, a weak antibody response was recorded in both serum and secretions. Antibody levels were undetectable in secretions at 31 days after infection. After primary intramuscular vaccination with killed virus, using sodium alginate as an adjuvant, antibody was detected only in the serum. However, following revaccination, a pronounced antibody response was demonstrated in both serum and secretions. Antibody was still detectable in all four ponies when tested 135 days later. Only a serum antibody response was detected in ponies after primary intramuscular vaccination with a commercial vaccine. Upon revaccination nasal antibody occurred in all ponies but this only persisted for about 30 days. Neither serum nor nasal antibody response occurred following intranasal vaccination and revaccination with a killed virus vaccine.
对接种或感染甲型马流感病毒2型的小马群体的血清和鼻分泌物中的抗体反应进行了检测。经气溶胶感染活病毒后，血清和分泌物中均记录到微弱的抗体反应。感染后31天，分泌物中未检测到抗体水平。用海藻酸钠作为佐剂，经肌肉初次接种灭活病毒后，仅在血清中检测到抗体。然而，再次接种后，血清和分泌物中均出现了明显的抗体反应。135天后检测时，所有四匹小马中仍可检测到抗体。用商业疫苗经肌肉初次接种小马后，仅检测到血清抗体反应。再次接种后，所有小马均出现鼻抗体，但仅持续约30天。用灭活病毒疫苗经鼻接种和再次接种后，血清和鼻抗体反应均未出现。
Zotero 插件