Rowlands D F, Freestone D S
J Hyg (Lond). 1971 Dec;69(4):579-86. doi: 10.1017/s0022172400021859.
This study of 724 13-year-old schoolgirls in the County Borough of Reading showed that approximately 25% were susceptible to rubella. 96.1% of the 129 seronegative girls and significant numbers of girls with low rubella HAI antibody titres responded to subcutaneous vaccination with Wistar RA. 27/3 rubella vaccine. The incidence of most reactions after vaccination was similar in those who responded to vaccine and those who were initially immune but did not develop rising antibody titres, but rash, lymphadenopathy and headache occurred significantly more frequently in the susceptible group.
这项针对雷丁郡自治市724名13岁女学生的研究表明,约25%的人对风疹易感。129名血清阴性女孩中的96.1%以及大量风疹血凝抑制(HAI)抗体滴度较低的女孩对Wistar RA 27/3风疹疫苗的皮下接种有反应。接种疫苗后,大多数反应的发生率在有反应的人群和最初免疫但抗体滴度未升高的人群中相似,但易感组出现皮疹、淋巴结病和头痛的频率明显更高。