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对雷丁市易感学龄女童进行风疹疫苗接种。

Vaccination against rubella of susceptible schoolgirls in Reading.

作者信息

Rowlands D F, Freestone D S

出版信息

J Hyg (Lond). 1971 Dec;69(4):579-86. doi: 10.1017/s0022172400021859.

DOI:10.1017/s0022172400021859
PMID:4257464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2131041/
Abstract

This study of 724 13-year-old schoolgirls in the County Borough of Reading showed that approximately 25% were susceptible to rubella. 96.1% of the 129 seronegative girls and significant numbers of girls with low rubella HAI antibody titres responded to subcutaneous vaccination with Wistar RA. 27/3 rubella vaccine. The incidence of most reactions after vaccination was similar in those who responded to vaccine and those who were initially immune but did not develop rising antibody titres, but rash, lymphadenopathy and headache occurred significantly more frequently in the susceptible group.

摘要

这项针对雷丁郡自治市724名13岁女学生的研究表明,约25%的人对风疹易感。129名血清阴性女孩中的96.1%以及大量风疹血凝抑制(HAI)抗体滴度较低的女孩对Wistar RA 27/3风疹疫苗的皮下接种有反应。接种疫苗后,大多数反应的发生率在有反应的人群和最初免疫但抗体滴度未升高的人群中相似,但易感组出现皮疹、淋巴结病和头痛的频率明显更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba6a/2131041/c329bfb237c4/jhyg00090-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba6a/2131041/c329bfb237c4/jhyg00090-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba6a/2131041/c329bfb237c4/jhyg00090-0077-a.jpg

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Rubella vaccination.

本文引用的文献

1
Diagnosis and management: congenital rubella.
Pediatrics. 1966 Feb;37(2):335-8.
2
Reinfection with rubella virus despite live vaccine induced immunity. Trials of HPV-77 and HPV-80 live rubella virus vaccines and subsequent artificial and natural challenge studies.尽管接种了风疹活疫苗获得了免疫力,但仍出现风疹病毒再感染。HPV - 77和HPV - 80风疹活疫苗的试验以及随后的人工和自然激发研究。
Am J Dis Child. 1969 Aug;118(2):275-94. doi: 10.1001/archpedi.1969.02100040277025.
3
Clinical and laboratory studies with rubella vaccines in adults.成人风疹疫苗的临床与实验室研究。
风疹疫苗接种
Br Med J. 1972 Aug 5;3(5822):305-6.
4
Rubella screening and immunization of schoolgirls: a long-term evaluation.女学生风疹筛查与免疫接种:长期评估
Br J Prev Soc Med. 1974 Feb;28(1):54-9. doi: 10.1136/jech.28.1.54.
5
Efficacy of rubella vaccination.风疹疫苗的效力
Br Med J. 1978 Sep 2;2(6138):697-8. doi: 10.1136/bmj.2.6138.697-c.
Br Med J. 1969 Feb 1;1(5639):271-6. doi: 10.1136/bmj.1.5639.271.
4
Rubella: reinfection of vaccinated and naturally immune persons exposed in an epidemic.风疹:在风疹流行期间,已接种疫苗者和自然免疫者再次感染。
N Engl J Med. 1970 Oct 8;283(15):771-8. doi: 10.1056/NEJM197010082831501.
5
Attenuated rubella viruses. Laboratory and clinical characteristics.减毒风疹病毒。实验室及临床特征
Am J Dis Child. 1969 Aug;118(2):155-65. doi: 10.1001/archpedi.1969.02100040157001.
6
Rubella vaccines.风疹疫苗
Br Med Bull. 1969 May;25(2):159-64. doi: 10.1093/oxfordjournals.bmb.a070686.