Downing J W, Buley R J, Brock-Utne J G, Houlton P C
Br J Anaesth. 1979 Feb;51(2):135-40. doi: 10.1093/bja/51.2.135.
Thirty mothers undergoing elective Caesarean section received thiopentone 3.5 mg kg-1 and 30 received etomidate 0.3 mg kg-1 for induction of anaesthesia. Subsequent management of anaesthesia was identical in both groups. Maternal to fetal base excess differences and the degree of biochemical correlation between mother and infant were more favourable following etomidate than following thiopentone. The clinical status of the newborn was considered superior with etomidate.
30例行择期剖宫产的产妇接受硫喷妥钠3.5毫克/千克诱导麻醉,30例接受依托咪酯0.3毫克/千克诱导麻醉。两组麻醉的后续管理相同。依托咪酯组产妇与胎儿碱剩余差值及母婴生化相关性程度均优于硫喷妥钠组。依托咪酯组新生儿的临床状况被认为更好。