King C S, Barton S P, Nicholls S, Marks R
Br J Dermatol. 1979 Feb;100(2):165-72. doi: 10.1111/j.1365-2133.1979.tb05556.x.
The constancy of stratum corneum thickness suggests an ordered decrease in intracorneal cohesion binding forces. In this study, intracorneal cohesion was measured in the vertical dimension by cohesography and the number of cells released after applying a standardized stimulus was determined before and after repeated stripping of the same sites with adhesive tape. In addition, surface replicas and the corneocytes from different levels were examined by scanning and transmission electron microscopy and differential phase interference microscopy. The results indicate a gradual loss of cohesion within the stratum corneum towards the surface and that anatomical changes take place in the corneocytes as they progress towards the surface.
角质层厚度的恒定表明角膜内聚力结合力呈有序下降。在本研究中,通过黏附力描记法在垂直维度测量角膜内聚力,并在使用胶带对同一部位进行重复剥离前后,测定施加标准化刺激后释放的细胞数量。此外,通过扫描电子显微镜、透射电子显微镜和微分相衬干涉显微镜检查了不同水平的表面复制品和角质形成细胞。结果表明,角质层内的凝聚力朝着表面逐渐丧失,并且角质形成细胞在向表面推进时会发生解剖学变化。