Bechelli L M, Gallego Garbajosa P, Gyi M M, Uemura K, Sundaresan T, Tamondong C, Martínez Domínguez V, Walter J
Bull World Health Organ. 1973;48(3):335-44.
In the WHO Leprosy BCG Trial in Burma a mass survey was undertaken to determine whether children had been exposed to patients with leprosy and, if so, the form of the index case. This paper presents the most important epidemiological data collected in this survey. The prevalence rate was 31.6 per 1 000. It seems that even if the prevalence rate is very high the L rate does not increase accordingly. The high T rates in areas of high endemicity seem to be related mainly to the degree of spreading of leprosy, even to persons who react to lepromin. Comparison of the results with data available for the area before the survey was made shows that 87% of the L cases had already been detected and that 54% of the T cases had not. There was a tendency for high L rates to be associated with high prevalence rates. The results do not suggest that any particular age group has greater susceptibility or resistance; the prevalence rates seemed to be related mainly to the age when exposure occurred. A higher prevalence of leprosy in males started to appear in the 10-14-year age group, and after the age of 15 the difference became impressive. Biological, socio-economic, and environmental factors seem to be responsible for the level of endemicity, which does not seem to be essentially or primarily related to ethnic origin.
在世界卫生组织于缅甸开展的麻风卡介苗试验中,进行了一次大规模调查,以确定儿童是否接触过麻风病人,若接触过,确定索引病例的类型。本文展示了此次调查收集到的最重要的流行病学数据。患病率为每1000人中有31.6人。即便患病率很高,L率似乎也不会相应增加。高流行区的高T率似乎主要与麻风病的传播程度有关,甚至与对麻风菌素呈反应的人有关。将此次调查结果与调查前该地区可得数据进行比较表明,87%的L型病例已被发现,而54%的T型病例未被发现。存在高L率与高患病率相关的趋势。结果并未表明任何特定年龄组易感性或抵抗力更强;患病率似乎主要与接触发生时的年龄有关。麻风病在男性中的较高患病率在10 - 14岁年龄组开始显现,15岁以后差异变得显著。生物、社会经济和环境因素似乎是造成流行程度的原因,而这似乎与种族出身并无本质或主要关联。