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1
Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible acid phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏酸性磷酸酶结构基因的鉴定。
Genetics. 1976 Oct;84(2):183-92. doi: 10.1093/genetics/84.2.183.
2
Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶缺陷型突变体的分离
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3
Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶结构基因的鉴定。
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4
The pho-2A mutant of Neurospora crassa which is deficient in Pi-repressible alkaline phosphatase (EC 3.1.3.1) is also defective in Pi-repressible acid phosphatase (EC 3.1.3.2).粗糙脉孢菌的pho-2A突变体缺乏磷酸根可阻遏的碱性磷酸酶（EC 3.1.3.1），在磷酸根可阻遏的酸性磷酸酶（EC 3.1.3.2）方面也存在缺陷。
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5
Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.脉孢菌中碱性磷酸酶合成的遗传控制：在显性研究中使用部分二倍体。
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6
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Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations.粗糙脉孢菌中磷酸盐代谢酶的遗传控制：调控突变之间的关系。
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Regulation of synthesis and secretion of acid and alkaline phosphatases in Neurospora crassa.粗糙脉孢菌中酸性和碱性磷酸酶合成与分泌的调控
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Nitrogen regulation of acid phosphatase in Neurospora crassa.粗糙脉孢菌中酸性磷酸酶的氮调节
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10
Genetic control of the synthesis of repressible phosphatases in Neurospora crassa.粗糙脉孢菌中可阻遏磷酸酶合成的遗传控制。
Genetics. 1971 Nov;69(3):339-51. doi: 10.1093/genetics/69.3.339.

引用本文的文献

1
Itaconic acid production is regulated by LaeA in .衣康酸的产生在……中受LaeA调控。 （原句中“in”后面缺少具体内容）
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Fungal traits that drive ecosystem dynamics on land.驱动陆地生态系统动态变化的真菌特性。
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Short communication: Purification and properties of acid phosphatase (EC 3.1.3.2) secreted by strain 74A of the mould Neurospora crassa.短讯：粗糙脉孢菌 74A 菌株分泌的酸性磷酸酶（EC 3.1.3.2）的纯化和性质。
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5
Repressible extracellular phosphodiesterases showing cyclic 2',3'- and cyclic 3',5'-nucleotide phosphodiesterase activities in Neurospora crassa.在粗糙脉孢菌中表现出2',3'-环核苷酸和3',5'-环核苷酸磷酸二酯酶活性的可阻遏细胞外磷酸二酯酶。
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6
Chromosomal loci of Neurospora crassa.粗糙脉孢菌的染色体位点。
Microbiol Rev. 1982 Dec;46(4):426-570. doi: 10.1128/mr.46.4.426-570.1982.
7
Nitrogen regulation of acid phosphatase in Neurospora crassa.粗糙脉孢菌中酸性磷酸酶的氮调节
J Bacteriol. 1980 Mar;141(3):1470-3. doi: 10.1128/jb.141.3.1470-1473.1980.
8
Regulation of synthesis and secretion of acid and alkaline phosphatases in Neurospora crassa.粗糙脉孢菌中酸性和碱性磷酸酶合成与分泌的调控
Curr Genet. 1987;11(6-7):521-7. doi: 10.1007/BF00384615.
9
Characterization of cpd-1 and cpd-2 mutants which affect the activity of orthophosphate regulated cyclic phosphodiesterase in Neurospora.影响粗糙脉孢菌中正磷酸调节的环磷酸二酯酶活性的cpd-1和cpd-2突变体的特性分析。
Curr Genet. 1985;10(3):197-203. doi: 10.1007/BF00798749.
10
Mutations affecting cyclic phosphodiesterases and adenylate cyclase in Neurospora.影响粗糙脉孢菌中环磷酸二酯酶和腺苷酸环化酶的突变
Curr Genet. 1986;10(12):893-901. doi: 10.1007/BF00398286.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Isolation and chemical properties of a repressible acid phosphatase in Neurospora crassa.粗糙脉孢菌中一种可阻遏酸性磷酸酶的分离及化学性质
J Biol Chem. 1971 Mar 10;246(5):1419-25.
3
Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶缺陷型突变体的分离
Genetics. 1974 Oct;78(2):645-59. doi: 10.1093/genetics/78.2.645.
4
Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.脉孢菌中碱性磷酸酶合成的遗传控制：在显性研究中使用部分二倍体。
Genetics. 1974 May;77(1):25-43. doi: 10.1093/genetics/77.1.25.
5
Repressible extracellular nucleases in Neurospora crassa.粗糙脉孢菌中可抑制的细胞外核酸酶
Biochim Biophys Acta. 1973 Sep 7;319(3):288-93. doi: 10.1016/0005-2787(73)90168-8.
6
Genetic regulation of phosphate transport system II in Neurospora.粗糙脉孢菌中磷酸盐转运系统II的遗传调控
Biochim Biophys Acta. 1975 Nov 17;413(1):95-103. doi: 10.1016/0005-2736(75)90061-9.

粗糙脉孢菌中磷酸盐代谢的调控：可阻遏酸性磷酸酶结构基因的鉴定。

Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible acid phosphatase.

作者信息

Nelson R E, Lehman J F, Metzenberg R L

出版信息

Genetics. 1976 Oct;84(2):183-92. doi: 10.1093/genetics/84.2.183.

DOI:10.1093/genetics/84.2.183
PMID:137163
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213571/
Abstract

A mutant of Neurospora crassa with an altered repressible acid phosphatase has been isolated. The enzyme is much more thermolabile than that of wild type, and has an increased Michaelis constant. Tests of allelic interactions (in partial diploids) and in vitro mixing experiments were consistent with the mutation being in the structural gene for the enzyme. This gene, pho-3, was found to be located in the right arm of Linkage Group IV (LGIV). Thus, pho-3 and the structural gene for repressible alkaline phosphatase, pho-2 (LG V), map in separate linkage groups and cannot be part of the same operon. Neither of these structural genes is linked to the known regulatory genes, nuc-1 (LG I), nuc-2 (LG II), and preg (LG II).

摘要

已分离出一种粗糙脉孢菌的突变体，其可阻遏酸性磷酸酶发生了改变。该酶比野生型的酶对热更不稳定，且米氏常数增加。等位基因相互作用测试（在部分二倍体中）和体外混合实验表明，该突变位于该酶的结构基因中。发现这个基因pho - 3位于连锁群IV（LGIV）的右臂。因此，pho - 3和可阻遏碱性磷酸酶的结构基因pho - 2（LG V）位于不同的连锁群中，不可能是同一操纵子的一部分。这两个结构基因均与已知的调控基因nuc - 1（LG I）、nuc - 2（LG II）和preg（LG II）不连锁。