• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations.粗糙脉孢菌中磷酸盐代谢酶的遗传控制：调控突变之间的关系。
Genetics. 1975 Mar;79(3):419-34. doi: 10.1093/genetics/79.3.419.
2
Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.脉孢菌中碱性磷酸酶合成的遗传控制：在显性研究中使用部分二倍体。
Genetics. 1974 May;77(1):25-43. doi: 10.1093/genetics/77.1.25.
3
Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶缺陷型突变体的分离
Genetics. 1974 Oct;78(2):645-59. doi: 10.1093/genetics/78.2.645.
4
Regulation of phosphate metabolism in Neurospora crassa. Characterization of regulatory mutants.粗糙脉孢菌中磷酸盐代谢的调控。调控突变体的特性
Genetics. 1973 Sep;75(1):61-73. doi: 10.1093/genetics/75.1.61.
5
Genetic regulation of phosphate transport system II in Neurospora.粗糙脉孢菌中磷酸盐转运系统II的遗传调控
Biochim Biophys Acta. 1975 Nov 17;413(1):95-103. doi: 10.1016/0005-2736(75)90061-9.
6
Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible acid phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏酸性磷酸酶结构基因的鉴定。
Genetics. 1976 Oct;84(2):183-92. doi: 10.1093/genetics/84.2.183.
7
Control of the Production of orthophosphate repressible extracellular enzymes in Neurospora crassa.粗糙脉孢菌中正磷酸可阻遏的胞外酶产生的调控
Mol Gen Genet. 1977 Feb 28;151(1):5-10. doi: 10.1007/BF00446906.
8
The structural gene for a phosphorus-repressible phosphate permease in Neurospora crassa can complement a mutation in positive regulatory gene nuc-1.粗糙脉孢菌中一种受磷抑制的磷酸盐通透酶的结构基因可弥补正向调节基因nuc-1中的突变。
Mol Cell Biol. 1988 Mar;8(3):1376-9. doi: 10.1128/mcb.8.3.1376-1379.1988.
9
Acid phosphatase (EC 3.1.3.2) synthesis by phosphorus regulatory mutant strains of Neurospora crassa.粗糙脉孢菌磷调节突变菌株的酸性磷酸酶（EC 3.1.3.2）合成
Braz J Med Biol Res. 1989;22(4):423-31.
10
Genetic control of the synthesis of repressible phosphatases in Neurospora crassa.粗糙脉孢菌中可阻遏磷酸酶合成的遗传控制。
Genetics. 1971 Nov;69(3):339-51. doi: 10.1093/genetics/69.3.339.

引用本文的文献

1
Core regulatory components of the PHO pathway are conserved in the methylotrophic yeast Hansenula polymorpha.磷酸饥饿应答（PHO）途径的核心调控组件在甲基营养型酵母多形汉逊酵母中是保守的。
Curr Genet. 2016 Aug;62(3):595-605. doi: 10.1007/s00294-016-0565-7. Epub 2016 Jan 21.
2
Linkage relationships between regulatory and structural gene loci involved in zein synthesis in maize.玉米醇溶蛋白合成相关调控基因和结构基因座之间的连锁关系。
Theor Appl Genet. 1978 Nov;52(6):263-7. doi: 10.1007/BF00303503.
3
Positive regulatory elements involved in urea amidolyase and urea uptake induction in Saccharomyces cerevisiae.参与酵母属酿酒酵母中尿素 amidolyase 和尿素摄取诱导的正调控元件。
Curr Genet. 1981 Sep;4(1):13-8. doi: 10.1007/BF00376780.
4
Cooperative action of the NIT2 and NIT4 transcription factors upon gene expression in Neurospora crassa.粗糙脉孢菌中NIT2和NIT4转录因子对基因表达的协同作用。
Curr Genet. 2003 Feb;42(5):260-7. doi: 10.1007/s00294-002-0362-3. Epub 2003 Jan 14.
5
A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: possible role in G protein-coupled signal transduction.一种嗜异源性和多嗜性鼠白血病病毒的人细胞表面受体：在G蛋白偶联信号转导中的可能作用。
Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1385-90. doi: 10.1073/pnas.96.4.1385.
6
NUC-2, a component of the phosphate-regulated signal transduction pathway in Neurospora crassa, is an ankyrin repeat protein.NUC-2是粗糙脉孢菌中磷酸盐调节信号转导途径的一个组成部分，是一种锚蛋白重复序列蛋白。
Mol Gen Genet. 1996 Oct 28;252(6):709-16. doi: 10.1007/BF02173977.
7
Insertional mutagenesis in Neurospora crassa: cloning and molecular analysis of the preg+ gene controlling the activity of the transcriptional activator NUC-1.粗糙脉孢菌中的插入诱变：控制转录激活因子NUC-1活性的preg+基因的克隆与分子分析
Genetics. 1993 Feb;133(2):193-202. doi: 10.1093/genetics/133.2.193.
8
In vitro synthesis of repressible yeast acid phosphatase: identification of multiple mRNAs and products.可阻遏酵母酸性磷酸酶的体外合成：多种mRNA和产物的鉴定
Proc Natl Acad Sci U S A. 1980 Aug;77(8):4504-8. doi: 10.1073/pnas.77.8.4504.
9
Function of positive regulatory gene gal4 in the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae: evidence that the GAL81 region codes for part of the gal4 protein.正调控基因gal4在酿酒酵母半乳糖途径酶合成中的作用：GAL81区域编码gal4蛋白一部分的证据。
J Bacteriol. 1980 Feb;141(2):508-27. doi: 10.1128/jb.141.2.508-527.1980.
10
Isolation and characterization of mutants that produce the allantoin-degrading enzymes constitutively in Saccharomyces cerevisiae.酿酒酵母中组成型产生尿囊素降解酶的突变体的分离与鉴定。
Mol Cell Biol. 1982 Sep;2(9):1088-95. doi: 10.1128/mcb.2.9.1088-1095.1982.

本文引用的文献

1
An insertional translocation in neurospora that generates duplications heterozygous for mating type.在 Neurospora 中发生的插入易位，产生了杂合子的交配型重复。
Genetics. 1972 May;71(1):25-51. doi: 10.1093/genetics/71.1.25.
2
A repressible acid phosphatase in Neurospora crassa.粗糙脉孢菌中的一种可阻遏酸性磷酸酶。
Biochem Biophys Res Commun. 1967 Apr 20;27(2):183-8. doi: 10.1016/s0006-291x(67)80059-7.
3
Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae.酿酒酵母酸性磷酸酶突变体的分离与鉴定
J Bacteriol. 1973 Feb;113(2):727-38. doi: 10.1128/jb.113.2.727-738.1973.
4
Uninducible mutants in the gal i locus of Saccharomyces cerevisiae.酿酒酵母半乳糖激酶基因座中的不可诱导突变体。
J Bacteriol. 1972 Mar;109(3):1139-43. doi: 10.1128/jb.109.3.1139-1143.1972.
5
Genetic control of the synthesis of repressible phosphatases in Neurospora crassa.粗糙脉孢菌中可阻遏磷酸酶合成的遗传控制。
Genetics. 1971 Nov;69(3):339-51. doi: 10.1093/genetics/69.3.339.
6
Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶缺陷型突变体的分离
Genetics. 1974 Oct;78(2):645-59. doi: 10.1093/genetics/78.2.645.
7
Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.脉孢菌中碱性磷酸酶合成的遗传控制：在显性研究中使用部分二倍体。
Genetics. 1974 May;77(1):25-43. doi: 10.1093/genetics/77.1.25.
8
Regulation of phosphate metabolism in Neurospora crassa. Characterization of regulatory mutants.粗糙脉孢菌中磷酸盐代谢的调控。调控突变体的特性
Genetics. 1973 Sep;75(1):61-73. doi: 10.1093/genetics/75.1.61.
9
Simple and reliable method for replica plating Neurospora crassa.用于粗糙脉孢菌影印接种的简单可靠方法。
J Bacteriol. 1972 Jun;110(3):1017-21. doi: 10.1128/jb.110.3.1017-1021.1972.

粗糙脉孢菌中磷酸盐代谢酶的遗传控制：调控突变之间的关系。

Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations.

作者信息

Littlewood B S, Chia W, Metzenberg R L

出版信息

Genetics. 1975 Mar;79(3):419-34. doi: 10.1093/genetics/79.3.419.

DOI:10.1093/genetics/79.3.419
PMID:123873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213282/
Abstract

In Neurospora crassa, the phosphate-metabolizing enzymes are made during phosphate starvation, but not under phosphate sufficiency. The synthesis of these enzymes is controlled by three regulatory genes: pcon-nuc-2, preg and nuc-1, pcon-nuc-2 and preg are closely linked. A model of the hierarchical relationships among these regulatory genes is presented. Studies of double mutants and revertants confirm several predictions of the model. It has been found that nuc-2 (null) and pcon-c (constitutive) mutations reside in the same cistron. preg-c (constitutive) mutations are epistatic to nuc-2 mutations. nuc-1 (null) mutations are epistatic to all others.

摘要

在粗糙脉孢菌中，磷酸盐代谢酶是在磷酸盐饥饿期间产生的，但在磷酸盐充足的情况下则不会产生。这些酶的合成受三个调控基因控制：pcon-nuc-2、preg和nuc-1，pcon-nuc-2和preg紧密连锁。本文提出了这些调控基因之间层次关系的模型。对双突变体和回复体的研究证实了该模型的几个预测。已发现nuc-2（无效）和pcon-c（组成型）突变位于同一顺反子中。preg-c（组成型）突变对nuc-2突变呈上位性。nuc-1（无效）突变对所有其他突变呈上位性。