豚鼠骨骼肌体外前列腺素的生物合成以及雌二醇-17β和孕酮的影响。
Prostaglandin biosynthesis by guinea-pig skeletal muscle in vitro and the effect of oestradiol-17 beta and progesterone.
作者信息
Kerry P J
出版信息
Br J Pharmacol. 1979 Mar;65(3):447-50. doi: 10.1111/j.1476-5381.1979.tb07849.x.
Abstract
- The effect of oestradiol and progesterone on prostaglandin biosynthesis by guinea-pig skeletal muscle in vitro has been investigated. 2. At high concentrations, oestradiol-17 beta (100 microgram/ml) and progesterone (500 microgram/ml) increased prostaglandin E and prostaglandin F synthesis (measured by radioimmunoassay). 3. It is suggested that these steroids are unlikely to be found in vivo at levels sufficient to influence prostaglandin synthesis by skeletal muscle in physiological and pathological situations.
摘要
- 研究了雌二醇和孕酮对豚鼠骨骼肌体外前列腺素生物合成的影响。2. 在高浓度下，17β-雌二醇（100微克/毫升）和孕酮（500微克/毫升）增加了前列腺素E和前列腺素F的合成（通过放射免疫测定法测量）。3. 有人认为，在生理和病理情况下，体内不太可能出现足以影响骨骼肌前列腺素合成的这些类固醇水平。
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本文引用的文献
1
Reduction of prostaglandin E2 to prostaglandin F2alpha by an enzyme in sheep blood.绵羊血液中的一种酶将前列腺素E2还原为前列腺素F2α 。
Biochim Biophys Acta. 1974 Apr 26;348(1):145-54. doi: 10.1016/0005-2760(74)90100-3.
2
Letter to the editor: A solvent system for thin layer chromatographic separation of prostaglandins and blood pigment.致编辑的信：一种用于前列腺素和血液色素薄层色谱分离的溶剂系统。
Prostaglandins. 1974 Aug 10;7(3):207-8. doi: 10.1016/0090-6980(74)90003-3.
3
Preparative thin-layer and column chromatography of prostaglandins.前列腺素的制备型薄层色谱法和柱色谱法。
J Lipid Res. 1969 May;10(3):316-9.
4
Anti-inflammatory effects of estradiol on human blood leukocytes.雌二醇对人体血液白细胞的抗炎作用。
J Lab Clin Med. 1972 Sep;80(3):373-84.
5
The development of antisera to prostaglandins B2 and F2alpha and their analysis using solid-phase and double antibody radioimmunoassay methods.前列腺素B2和F2α抗血清的研制及其用固相和双抗体放射免疫分析法进行的分析。
Br J Pharmacol. 1975 Dec;55(4):503-14. doi: 10.1111/j.1476-5381.1975.tb07425.x.
6
Effects of oestradiol and progesterone on the in vitro production of prostaglandin F2alpha by the guinea-pig uterus.雌二醇和孕酮对豚鼠子宫体外产生前列腺素F2α的影响。
Br J Pharmacol. 1975 Oct;55(2):229-32. doi: 10.1111/j.1476-5381.1975.tb07632.x.
7
Prostaglandin production by a mild inflammatory lesion in sheep.绵羊轻度炎症损伤产生前列腺素的情况。
Br J Pharmacol. 1975 Feb;53(2):305-7. doi: 10.1111/j.1476-5381.1975.tb07363.x.
8
Effect of p-bromophenacyl bromide, an inhibitor of phospholipase A2, on arachidonic acid release and prostaglandin synthesis by the guinea-pig uterus in vitro.对溴苯甲酰溴（一种磷脂酶A2抑制剂）对豚鼠子宫体外花生四烯酸释放和前列腺素合成的影响。
Br J Pharmacol. 1977 Jan;59(1):107-13. doi: 10.1111/j.1476-5381.1977.tb06983.x.
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The metabolism of prostaglandins by the guinea-pig uterus with particular reference to corpus luteal maintenance in early pregnancy.豚鼠子宫对前列腺素的代谢，特别涉及妊娠早期黄体的维持。
Br J Pharmacol. 1978 Feb;62(2):177-83. doi: 10.1111/j.1476-5381.1978.tb08443.x.
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