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骨关节炎中关节软骨蛋白聚糖的可提取性增强。

Enhanced extractability of articular cartilage protoglycans in osteoarthrosis.

作者信息

Brandt K D

出版信息

Biochem J. 1974 Nov;143(2):475-8. doi: 10.1042/bj1430475.

DOI:10.1042/bj1430475
PMID:4282471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1168407/
Abstract

Tissue contents of small, easily extracted, proteoglycans, relatively poor in keratan sulphate, were compared in normal and osteoarthrotic cartilage. Although the amounts of small proteoglycans were similar in each tissue, as were the collagen contents, some proteoglycans in the diseased cartilage were much more readily extracted than those in the normal tissue.

摘要

对正常和骨关节炎软骨中含量较少、易于提取、硫酸角质素相对较少的蛋白聚糖的组织含量进行了比较。尽管每个组织中小蛋白聚糖的含量相似，胶原蛋白含量也相似，但患病软骨中的一些蛋白聚糖比正常组织中的更容易提取。

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本文引用的文献

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Biochem J. 1971 Jan;121(2):261-70. doi: 10.1042/bj1210261.
5
The molecular weight of chondroitin sulphate from human articular cartilage. Effect of age and of osteoarthritis.人关节软骨硫酸软骨素的分子量。年龄和骨关节炎的影响。
Calcif Tissue Res. 1972;10(1):31-7. doi: 10.1007/BF02012533.
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