Singh L, Purdom I F, Jones K W
Chromosoma. 1979 Feb 21;71(2):167-81. doi: 10.1007/BF00292821.
Sex chromosome associated satellite DNAs is isolated from the snakes Elaphe radiata (sat III) (Singh et al., 1976) and Bungarus fasciatus (Elapidae) (minor satellite) are evolutionarily conserved throughout the suborder Ophidia. An autosome limited satellite DNA (B. fasciatus major satellite) is not similarly conserved. Both types of satellites have been studied by in situ hybridisation in various somatic tissues and germ cells where it has been observed that the W sex chromosome remains condensed in interphase nuclei. In growing oocytes however, the W chromosome satellite rich heterochromatin decondenses completely whilst the autosomal satellite rich regions remain condensed. Later, the cycle is reversed and the W chromosome condenses whilst the autosomal satellite regions decondense. In a primitive snake (Eryx johni johni) where the sex chromosomes are not differentiated and where there is no satellite DNA specific to them, these phenomena are absent. - The differential behaviour of autosomal and sex chromosome associated satellite DNAs is discussed in the light of gene regulation.
与性染色体相关的卫星DNA是从辐射锦蛇（卫星III）（辛格等人，1976年）和银环蛇（眼镜蛇科）（小卫星）中分离出来的，在整个蛇亚目中进化上是保守的。一种常染色体限制性卫星DNA（银环蛇主要卫星）则没有类似的保守性。这两种类型的卫星都已通过原位杂交在各种体细胞组织和生殖细胞中进行了研究，在这些细胞中观察到W性染色体在间期核中保持浓缩状态。然而，在生长中的卵母细胞中，富含W染色体卫星的异染色质完全解聚，而富含常染色体卫星的区域则保持浓缩状态。后来，这个过程逆转，W染色体浓缩，而常染色体卫星区域解聚。在一种原始蛇（红沙蟒）中，其性染色体没有分化，也没有特定于它们的卫星DNA，这些现象不存在。——根据基因调控对常染色体和与性染色体相关的卫星DNA的差异行为进行了讨论。
