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D群溶血素链球菌溶素S和磷脂酶C对全细胞和原生质球的作用。

Action of streptolysin S, the group D hemolysin, and phospholipase C on whole cells and spheroplasts.

作者信息

Davie J M, Brock T D

出版信息

J Bacteriol. 1966 Feb;91(2):595-600. doi: 10.1128/jb.91.2.595-600.1966.

Abstract

Davie, Joseph M. (Indiana University, Bloomington), and Thomas D. Brock. Action of streptolysin S, the group D hemolysin, and phospholipase C on whole cells and spheroplasts. J. Bacteriol. 91:595-600. 1966.-The effect of streptolysin S, the group D hemolysin, and phospholipase C (the alpha toxin of Clostridium perfringens) on whole cells and spheroplasts or protoplasts of three strains of streptococci and Micrococcus lysodeikticus was tested. Viability, C(14)-glycine uptake, and lysis were measured. The group D hemolysin and phospholipase C were active against whole bacteria; streptolysin S was not. All three substances were active on spheroplasts. A partially resistant mutant derived from a strain sensitive to the group D hemolysin was also partially resistant to streptolysin S and phospholipase C. Antimycin A protected spheroplasts from streptolysin S but not from the group D hemolysin.

摘要

戴维,约瑟夫·M.(印第安纳大学,布卢明顿分校),以及托马斯·D.布罗克。D群溶血素链球菌溶素S和磷脂酶C对全细胞及原生质球的作用。《细菌学杂志》91:595 - 600。1966年。——测试了D群溶血素链球菌溶素S和磷脂酶C(产气荚膜梭菌的α毒素)对三株链球菌和溶壁微球菌的全细胞、原生质球或原生质体的影响。测定了存活率、C(14)-甘氨酸摄取量和细胞裂解情况。D群溶血素和磷脂酶C对完整细菌有活性;链球菌溶素S则无。所有这三种物质对原生质球均有活性。从一株对D群溶血素敏感的菌株衍生出的一个部分抗性突变体,对链球菌溶素S和磷脂酶C也有部分抗性。抗霉素A可保护原生质球免受链球菌溶素S的作用,但不能保护其免受D群溶血素的作用。

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