Das K, Patnaik B K
Gerontology. 1979;25(1):9-15. doi: 10.1159/000212315.
The endogenous oxygen uptake and the uptake with added substrate of whole-brain and mid-brain homogenates were significantly lower in older lizards as compared to younger. Both whole brain and mid-brain showed responses to cold stress for different lengths of time but the decline in oxygen uptake was more pronounced in the younger age-group. Respiratory rate and response to cold stress were more marked in the mid-brain than in the whole brain. Basing on earlier reports on mammals and on the present findings, it is suggested that the decline in physiological adaptation in older animals may be a general feature in vertebrates.
与年轻蜥蜴相比，老年蜥蜴全脑和中脑匀浆的内源性氧摄取以及添加底物后的氧摄取显著降低。全脑和中脑在不同时长内均表现出对冷应激的反应，但氧摄取的下降在较年轻年龄组中更为明显。中脑的呼吸速率和对冷应激的反应比全脑更为显著。基于早期关于哺乳动物的报道以及当前的研究结果，有人提出老年动物生理适应性的下降可能是脊椎动物的一个普遍特征。
