肺泡巨噬细胞产生干扰素。
Production of interferon by alveolar macrophages.
作者信息
Acton J D, Myrvik Q N
出版信息
J Bacteriol. 1966 Jun;91(6):2300-4. doi: 10.1128/jb.91.6.2300-2304.1966.
Abstract
Acton, Jean D. (Bowman Gray School of Medicine, Winston-Salem, N.C.), and Quentin N. Myrvik. Production of interferon by alveolar macrophages. J. Bacteriol. 91:2300-2304. 1966.-Rabbit alveolar macrophages inoculated with parainfluenza-3 virus in vitro produce a viral inhibitor which possesses the properties of interferon. The interferon is nondialyzable, is stable at pH 4, is not sedimented at 100,000 x g, exhibits species specificity, and can passively protect other alveolar macrophages from infection with virulent rabbitpox virus. The possible significance of alveolar macrophage-produced interferon is discussed.
摘要
阿克顿，让·D.（北卡罗来纳州温斯顿 - 塞勒姆市鲍曼·格雷医学院），以及昆廷·N.米尔维克。肺泡巨噬细胞产生干扰素。《细菌学杂志》91:2300 - 2304。1966年。——体外接种副流感3型病毒的兔肺泡巨噬细胞产生一种具有干扰素特性的病毒抑制剂。该干扰素不可透析，在pH 4时稳定，在100,000×g离心力下不沉淀，具有种属特异性，并且能够被动保护其他肺泡巨噬细胞免受强毒兔痘病毒的感染。文中讨论了肺泡巨噬细胞产生的干扰素的可能意义。
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